NDLI: Contrast Sensitivity versus Visual Evoked Potentials in Multiple Sclerosis.

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Contrast Sensitivity versus Visual Evoked Potentials in Multiple Sclerosis.

Content Provider	Europe PMC
Author	Shandiz, Javad Heravian Nourian, Abbas Hossaini, Mercedeh Bahr Moghaddam, Hadi Ostadi yekta, Abbas-Ali Sharifzadeh, Laleh Marouzi, Parviz
Copyright Year	2010
Abstract	PurposeTo compare the Cambridge contrast sensitivity (CS) test and visual evoked potentials (VEP) in detecting visual impairment in a population of visually symptomatic and asymptomatic patients affected by clinically definite multiple sclerosis (MS).MethodsFifty patients (100 eyes) presenting with MS and 25 healthy subjects (50 eyes) with normal corrected visual acuity were included in this study. CS was determined using the Cambridge Low Contrast Grating test and VEP was obtained in all eyes. Findings were evaluated in two age strata of 10–29 and 30–49 years.ResultsOf the 42 eyes in the 10–29 year age group, CS was abnormal in 22 (52%), VEP was also abnormal in 22 (52%), but only 12 eyes (28%) had visual symptoms. Of the 58 eyes in the 30–49 year group, CS was abnormal in 7 (12%), VEP was abnormal in 34 (58%), while only 11 eyes were symptomatic. No single test could detect all of the abnormal eyes.ConclusionThe Cambridge Low Contrast Grating test is useful for detection of clinical and subclinical visual dysfunction especially in young patients with multiple sclerosis. Nevertheless, only a combination of CS and VEP tests can detect most cases of visual dysfunction associated with MS.
ISSN	20082010
Journal	Journal of Ophthalmic & Vision Research
Volume Number	5
PubMed Central reference number	PMC3379913
Issue Number	3
PubMed reference number	22737353
e-ISSN	2008322X
Language	English
Publisher	Ophthalmic Research Center
Publisher Date	2010-07-01
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Subject Keyword	Visual Evoked Potential Contrast Sensitivity Multiple Sclerosis
Content Type	Text
Resource Type	Article
Subject	Ophthalmology

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