Effect of Acute Maximal Exercise on Circulating Levels of Interleukin-12 during Ramadan Fasting.

Content Provider	Europe PMC
Author	Abedelmalek, Salma Souissi, Nizar Takayuki, Akimoto Hadouk, Sami Tabka, Zouhair
Copyright Year	2011
Abstract	PurposeThe purpose of this study was to examine the effects of Ramadan fasting on circulating levels of interleukin-12 (IL-12) after a brief maximal exercise.MethodsNine subjects performed a Wingate test on three different occasions: (i) the first week of Ramadan (1WR), (ii) the fourth week of Ramadan (4WR), and (iii) three weeks after Ramadan (AR). Blood samples were taken before, immediately and 60 min after the exercise. Plasma concentrations of IL-12 were measured using enzyme-linked immunosorbent assay. Variance analysis revealed no significant effect of Ramadan on Ppeak and Pmean during the three testing periods.ResultsConsidering the effect of Ramadan on plasma concentrations of IL-12, analysis of the variance revealed a significant Ramadan effect (F(2, 16)=66.27; P < 0.001) as well as a significant time effect (F(2, 16)= 120.66; P < 0.001). However, no significant (Ramadan × time) of test interaction (F(4, 32)=2.40; P>0.05). For all measures, IL-12 levels were lower during 1WR and 4WR in comparison with AR (P < 0.05). Considering the exercise effects, IL-12 levels measured immediately after the exercise were significantly higher than those measured before and at 60 minutes after the exercise (P < 0.001).ConclusionsThese results suggest that an acute intense exercise-induced IL-12 response is modified by daytime fasting and modifications in sleep schedule during Ramadan.
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ISSN	2008000X
Journal	Asian Journal of Sports Medicine [Asian J Sports Med]
Volume Number	2
PubMed Central reference number	PMC3289209
Issue Number	3
PubMed reference number	22375234
e-ISSN	20087209
DOI	10.5812/asjsm.34751
Language	English
Publisher	Tehran University of Medical Sciences
Publisher Date	2011-09-01
Access Restriction	Open
Rights License	This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. © 2011 Sports Medicine Research Center, Tehran University of Medical Sciences
Subject Keyword	Ramadan Wingate Test Interleukin-12 Immunity Sleep Deprivation
Content Type	Text
Resource Type	Article
Subject	Orthopedics and Sports Medicine Sports Science