NDLI: Major clinical research advances in gynecologic cancer in 2011.

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Major clinical research advances in gynecologic cancer in 2011.

Content Provider	Europe PMC
Author	Suh, Dong Hoon Kim, Kidong Kim, Jae Weon
Copyright Year	2012
Abstract	The annual review of 2011 comprised 11 themes of major research achievements in gynecologic oncology including breast cancer. A potential paradigm shift in the management of ovarian cancer was reviewed through comprehensive genomic analyses and a tumor-specific new intraoperative fluorescence imaging technique using folate receptor-α targeted agent, which is expected to improve intraoperative staging and more radical cytoreduction. In addition, updates of bevacizumab and poly (ADP-ribose) polymerase inhibitors, risk-reducing salpingo-oophorectomy, and risk evaluation of pelvic mass were discussed. Regarding cervical cancer, this review covered new findings on human papillomavirus vaccines and human papillomavirus tests as well as the current status of clinical trials on locally advanced cervical cancer. The promising role of sentinel lymph node biopsy in the management of early stage endometrial cancer was followed by two notable clinical researches on: exemestane, an aromatase inhibitor, for the prevention of breast cancer and eribulin, a non-taxane microtubule dynamics inhibitor for the treatment of metastatic breast cancer. Lastly, in premenopausal women with breast cancer, the effect of gonadotropin-releasing hormone analogue on the occurrence of chemotherapy-induced early menopause was discussed.
ISSN	20050380
Journal	Journal of Gynecologic Oncology
Volume Number	23
PubMed Central reference number	PMC3280068
Issue Number	1
PubMed reference number	22355468
e-ISSN	20050399
DOI	10.3802/jgo.2012.23.1.53
Language	English
Publisher	Korean Society of Gynecologic Oncology and Colposcopy
Publisher Date	2012-01-09
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2012. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology
Subject Keyword	Breast cancer Comprehensive genomic analyses Gynecologic oncology Human papillomavirus vaccines Poly (ADP-ribose) polymerase inhibitors
Content Type	Text
Resource Type	Article
Subject	Oncology Obstetrics and Gynecology

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