Sleep disorder and cardiovascular risk factors among patients with type 2 diabetes mellitus.

Content Provider	Europe PMC
Author	Shim, Unjin Lee, Hyejin Oh, Jee-Young Sung, Yeon-Ah
Copyright Year	2011
Abstract	Background/AimsSleep disorder (SD) is associated with an increased risk of cardiovascular disease and is more prevalent among individuals with type 2 diabetes mellitus. These health problems not only frequently coexist but also exacerbate each other. We conducted a cross-sectional study to estimate the prevalence of SD among diabetic patients and to investigate the relationship between SD and cardiovascular risk among these patients.MethodsWe recruited 784 patients with type 2 diabetes and conducted a self-administered questionnaire. We assessed sleep quality using the Pittsburgh Sleep Quality Index and the risk of obstructive sleep apnea (OSA) using the Berlin Questionnaire. Additional information included blood pressure and metabolic profiles.ResultsOf the 784 diabetic patients, 301 (38.4%) patients had poor sleep quality, and 124 (15.8%) were at high risk for OSA. Patients at increased risk for OSA were more obese; they also had higher blood pressure, fasting plasma insulin levels, insulin resistance assessed by homeostasis model assessment (HOMA-IR), and serum triglycerides levels (p < 0.05). The frequency of risk for OSA was higher among obese patients compared with non-obese patients (34.8% vs. 9.4%, p < 0.05). Logistic regression analysis revealed that male sex and bone mass index were independent predictors of risk for OSA.ConclusionsSD was prevalent among type 2 diabetic patients, and OSA could aggravate their risk for cardiovascular disease. Clinical treatment of these patients should include evaluation and intervention for SD.
ISSN	12263303
Volume Number	26
PubMed Central reference number	PMC3192200
Issue Number	3
PubMed reference number	22016588
Journal	The Korean Journal of Internal Medicine [Korean J. Intern. Med]
e-ISSN	20056648
DOI	10.3904/kjim.2011.26.3.277
Language	English
Publisher	The Korean Association of Internal Medicine
Publisher Date	2011-09-13
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2011 The Korean Association of Internal Medicine
Subject Keyword	Cardiovascular diseases Sleep apnea, obstructive Diabetes mellitus, type 2
Content Type	Text
Resource Type	Article
Subject	Internal Medicine