Leptomeningeal metastases in a patient with an extragonadal germ cell tumor.

Content Provider	Europe PMC
Author	Kinebuchi, Yoshiaki Ishikawa, Masakuni Ishizuka, Osamu Nishizawa, Osamu Hongo, Kazuhiro
Copyright Year	2008
Abstract	We present a case of leptomeningeal metastases in a 30-year-old man with an extragonadal germ cell tumor. The patient was referred to our hospital for treatment of an occipital brain metastasis. This lesion was resected, followed by whole brain radiotherapy and further chemotherapy, and a temporary complete remission was achieved. However, leptomeningeal recurrence developed, and despite salvage chemotherapy, the patient died of disease. Although multidisciplinary treatment is given to treat brain metastases of germ cell tumors, the patients’ prognosis has been unsatisfactory. The identification of a standard/effective treatment is required.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3161680&blobtype=pdf
Volume Number	2
PubMed Central reference number	PMC3161680
PubMed reference number	21892301
Journal	Clinical Medicine. Oncology [Clin Med Oncol]
e-ISSN	11779314
DOI	10.4137/cmo.s687
Language	English
Publisher	Libertas Academica
Publisher Date	2008-04-24
Access Restriction	Open
Rights License	This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license http://creativecommons.org/licenses/by/3.0/). © 2008 the author(s), publisher and licensee Libertas Academica Ltd.
Subject Keyword	leptomeningeal metastasis brain metastasis germ cell tumor surgery chemotherapy
Content Type	Text
Resource Type	Article
Subject	Oncology