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Epidural needle with embedded optical fibers for spectroscopic differentiation of tissue: ex vivo feasibility study.
| Content Provider | Europe PMC |
|---|---|
| Author | Desjardins, Adrien E. Hendriks, Benno H.W. van der Voort, Marjolein Nachabé, Rami Bierhoff, Walter Braun, Guus Babic, Drazenko Rathmell, James P. Holmin, Staffan Söderman, Michael Holmström, Björn |
| Copyright Year | 2011 |
| Abstract | Epidural injection is commonly used to provide intraoperative anesthesia, postoperative and obstetric analgesia, and to treat acute radicular pain. Identification of the epidural space is typically carried out using the loss of resistance (LOR) technique, but the usefulness of this technique is limited by false LOR and the inability to reliably detect intravascular or subarachnoid needle placement. In this study, we present a novel epidural needle that allows for the acquisition of optical reflectance spectra from tissue close to the beveled surface. This needle has optical fibers embedded in the cannula that deliver and receive light. With two spectrometers, light received from tissue is resolved across the wavelength range of 500 to 1600 nm. To determine the feasibility of optical tissue differentiation, spectra were acquired from porcine tissues during a post mortem laminectomy. The spectra were processed with an algorithm that derives estimates of the hemoglobin and lipid concentrations. The results of this study suggest that the optical epidural needle has the potential to improve the accuracy of epidural space identification. |
| Journal | Biomedical Optics Express |
| Volume Number | 2 |
| PubMed Central reference number | PMC3114214 |
| Issue Number | 6 |
| PubMed reference number | 21698009 |
| e-ISSN | 21567085 |
| DOI | 10.1364/BOE.2.001452 |
| Language | English |
| Publisher | Optical Society of America |
| Publisher Date | 2011-05-06 |
| Access Restriction | Open |
| Rights License | This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially. ©2011 Optical Society of America |
| Subject Keyword | (170.3890) Medical optics instrumentation (170.6510) Spectroscopy, tissue diagnostics (170.6935) Tissue characterization |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biotechnology Atomic and Molecular Physics, and Optics |
