Laparoscopic restorative total proctocolectomy with ileal pouch anal anastomosis for familial adenomatous polyposis.

Content Provider	Europe PMC
Author	Palanivelu, C. Jani, Kalpesh Sendhilkumar, K. Parthasarathi, R. Senthilnathan, P. Maheshkumar, G.
Copyright Year	2008
Abstract	Background:Familial adenomatous polyposis is a hereditary disease characterized by the presence of thousands of colonic adenomas, which, if untreated, invariably undergo malignant transformation. Because this disease manifests at a young age, the laparoscopic approach to perform surgery would be desirable due to its cosmetic benefits. We describe our experience with this procedure and review the literature on the topic.Methods:This is a case series of 15 patients who underwent restorative proctocolectomy with ileo-anal pouch anastomosis for familial adenomatous polyposis between 2000 and 2007. The salient operative steps are described.Results:There were 9 males and 6 females, 32 to 52 years of age, with an average age of 44.8 years. The median body mass index was 21.5 (range, 17 to 28). Rectal cancer was already present in 4 patients at the time of diagnosis. The median operating time was 225 minutes. Mean blood loss was 60mL, with none of the patients requiring perioperative blood transfusion. None of the surgeries required conversion to the open approach. Bowel function resumed on the second postoperative day in 12 patients and on the third postoperative day in 3 patients. The median hospital stay was 8 days. Postoperatively, there was no mortality and no serious morbidity.Conclusion:Laparoscopic restorative proctocolectomy with ileal pouch anal anastomosis is a feasible surgery for familial adenomatous polyposis, and considering its cosmetic benefit, is a desirable option for this group of predominantly young patients.
ISSN	10868089
Journal	JSLS : Journal of the Society of Laparoendoscopic Surgeons
Volume Number	12
PubMed Central reference number	PMC3015866
Issue Number	3
PubMed reference number	18765048
e-ISSN	19383797
Language	English
Publisher	Society of Laparoendoscopic Surgeons
Publisher Date	2008-07-01
Publisher Place	Miami, FL
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits for noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited and is not altered in any way. © 2008 by JSLS, Journal of the Society of Laparoendoscopic Surgeons
Subject Keyword	Total proctocolectomy Ileal pouch-anal anastomosis Familial adenomatous polyposis
Content Type	Text
Resource Type	Article
Subject	Surgery