NDLI: Identification of single-nucleotide polymorphisms of the prion protein gene in sika deer (Cervus nippon laiouanus).

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Identification of single-nucleotide polymorphisms of the prion protein gene in sika deer (Cervus nippon laiouanus).

Content Provider	Europe PMC
Author	Jeong, Hyun-Jeong Lee, Joong-Bok Park, Seung-Yong Song, Chang-Seon Kim, Bo-Sook Rho, Jung-Rae Yoo, Mi-Hyun Jeong, Byung-Hoon Kim, Yong-Sun Choi, In-Soo
Copyright Year	2007
Abstract	Polymorphisms of the prion protein gene (PRNP) have been detected in several cervid species. In order to confirm the genetic variations, this study examined the DNA sequences of the PRNP obtained from 33 captive sika deer (Cervus nippon laiouanus) in Korea. A total of three single-nucleotide polymorphisms (SNPs) at codons 100, 136 and 226 in the PRNP of the sika deer were identified. The polymorphic site located at codon 100 has not been reported. The SNPs detected at codons 100 and 226 induced amino acid substitutions. The SNP at codon 136 was a silent mutation that does not induce any amino acid change. The genotype and allele frequencies were determined for each of the SNPs.
ISSN	1229845X
Journal	Journal of Veterinary Science
Volume Number	8
PubMed Central reference number	PMC2868139
Issue Number	3
PubMed reference number	17679779
e-ISSN	1976555X
DOI	10.4142/jvs.2007.8.3.299
Language	English
Publisher	The Korean Society of Veterinary Science
Publisher Date	2007-09-01
Access Restriction	Open
Rights License	This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2007 The Korean Society of Veterinary Science
Subject Keyword	PRNP sika deer single-nucleotide polymorphism
Content Type	Text
Resource Type	Article
Subject	Veterinary

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