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High defibrillation threshold: the science, signs and solutions.
| Content Provider | Europe PMC |
|---|---|
| Author | Jacob, Sony Pidlaoan, Victorio Singh, Jaspreet Bharadwaj, Aditya Patel, Mehul B Carrillo, Antonio |
| Abstract | Defibrillation threshold (DFT) testing has traditionally been an integral part of implantable cardioverter defibrillator (ICD) implantation. With the increasing number of patients receiving ICDs, physicians are encountering high DFT more often than before. Tackling the problem of high DFT, warrants an in-depth understanding of the science of defibrillation including the key electrophysiological concepts and the underlying molecular mechanisms. Numerous factors have been implicated in the causation of high DFT. Due consideration to the past medical history, pharmacotherapy, laboratory data and cardiac imaging, help in assessing the pre-procedural risk for occurrence of high DFT. Drugs, procedural changes, type and location of ICD lead system are some of the key players in predicting DFT during implantation. In the event of encountering an unacceptably high DFT, we recommend to follow a step-wise algorithm. Ruling out procedural complications like pneumothorax and tamponade is imperative before embarking on a search for potentially reversible clinical or metabolic derangements. Finally, if these attempts fail, the electrophysiologist must choose from a wide range of options for device adjustment and system modification. Although this review article is meant to be a treatise on the science, signs and solutions for high DFT, it is bound by limitations of space and scope of the article. |
| Journal | Indian Pacing and Electrophysiology Journal |
| Volume Number | 10 |
| PubMed Central reference number | PMC2803603 |
| Issue Number | 1 |
| PubMed reference number | 20084193 |
| e-ISSN | 09726292 |
| Language | English |
| Publisher | Indian Heart Rhythm Society |
| Publisher Date | 2010-01-07 |
| Access Restriction | Open |
| Rights License | This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright: © 2009 Jacob et al. |
| Subject Keyword | Defibrillation threshold testing DFT implantable cardioverter defibrillator |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physiology (medical) Cardiology and Cardiovascular Medicine |