NDLI: Serum and Ascitic Fluid Superoxide Dismutase and Malondialdehyde Levels in Patients with Cirrhosis.

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Serum and Ascitic Fluid Superoxide Dismutase and Malondialdehyde Levels in Patients with Cirrhosis.

Content Provider	Europe PMC
Author	Ozenirler, Seren Sancak, Banu Coskun, Ugur
Abstract	SummarySerum and ascitic fluid superoxide dismutase (SOD) and malondialdehyde (MDA) levels were measured in 43 patients with cirrhosis and in a 10 healthy control group.Compensated cirrhotic patients had no clinically detectable ascites, but decompensated patients had massive ascites. Cirrhotic patients were divided into three groups: patients with compensated cirrhosis (n = 16), patients with decompensated cirrhosis with Spontaneous bacterial peritonitis (SBP) (n = 14), and patients with decompensated cirrhosis without SBP (n = 13).All cirrhotic patients in the experimental group had significantly higher serum SOD (p < 0.001) and MDA levels (p < 0.01) than those in the control group. There were no significant differences with respect to serum SOD and MDA levels among the three different groups of patients. There was no remarkable difference in ascitic fluid SOD and MDA levels between decompensated cirrhotic patients with and without SBP (p > 0.05).These results suggest that the increase in serum SOD and MDA levels are not related to the presence of SBP and the status of liver cirrhosis. To sum up, clarifying the impact of increased serum SOD and MDA levels in cirrhotic patients needs further investigation.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC2688367&blobtype=pdf
Journal	Biomarker Insights [Biomark Insights]
Volume Number	3
PubMed Central reference number	PMC2688367
PubMed reference number	19578501
e-ISSN	11772719
DOI	10.4137/bmi.s639
Language	English
Publisher	Libertas Academica
Publisher Date	2008-03-12
Access Restriction	Open
Rights License	This article is published under the Creative Commons Attribution By licence. For further information go to: http://creativecommons.org/licenses/by/3.0. © 2008 by the authors
Subject Keyword	ascitic fluid liver cirrhosis malondialdehyde superoxide dismutase
Content Type	Text
Resource Type	Article
Subject	Biochemistry (medical) Molecular Medicine Pharmacology

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