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Neurodevelopment and endocrine disruption.
| Content Provider | Europe PMC |
|---|---|
| Author | Colborn, Theo |
| Abstract | In this article I explore the possibility that contaminants contribute to the increasing prevalence of attention deficit hyperactivity disorder, autism, and associated neurodevelopmental and behavioral problems in developed countries. I discuss the exquisite sensitivity of the embryo and fetus to thyroid disturbance and provide evidence of human in utero exposure to contaminants that can interfere with the thyroid. Because it may never be possible to link prenatal exposure to a specific chemical with neurodevelopmental damage in humans, I also present alternate models where associations have been made between exposure to specific chemicals or chemical classes and developmental difficulties in laboratory animals, wildlife, and humans. |
| ISSN | 00916765 |
| Journal | Environmental Health Perspectives |
| Volume Number | 112 |
| PubMed Central reference number | PMC1247186 |
| Issue Number | 9 |
| PubMed reference number | 15198913 |
| e-ISSN | 15529924 |
| DOI | 10.1289/ehp.6601 |
| Language | English |
| Publisher | National Institue of Environmental Health Sciences |
| Publisher Date | 2004-06-01 |
| Access Restriction | Open |
| Rights License | Publication of EHP lies in the public domain and is therefore without copyright. All text from EHP may be reprinted freely. Use of materials published in EHP should be acknowledged (for example, ?Reproduced with permission from Environmental Health Perspectives?); pertinent reference information should be provided for the article from which the material was reproduced. Articles from EHP, especially the News section, may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright. |
| Subject Keyword | ADHD autism behavior endocrine disruptor environmental contaminants neurologic effects prenatal exposure thyroid |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health |