Imaging, Treatment Options, Patient Selection, and Outcome Considerations for Patients With Bicuspid Aortic Valve Disease.

Content Provider	Europe PMC
Author	Ahmad, Yousif Agarwal, Vratika Williams, Matthew L. Wang, Dee Dee Reardon, Michael J. Cavalcante, João L. Makkar, Raj Forrest, John K.
Copyright Year	2022
Description	Transcatheter aortic valve replacement has emerged as a safe and effective alternative to surgical aortic valve replacement for patients with severe symptomatic aortic stenosis across the spectrum of surgical risks based on a series of foundational randomized clinical trials. Of note, patients with bicuspid aortic valve (BAV) disease were excluded from all these pivotal randomized trials, leaving a significant knowledge gap because BAVs are commonly encountered in patients referred for aortic valve surgery or intervention. In this comprehensive review, we aim to provide heart teams with a detailed insight into how to approach patients with BAV disease, focusing on imaging and characterization of bicuspid valves, an overview of surgical approaches, and an understanding of the current data behind the role of transcatheter aortic valve replacement for patients with BAV disease. Highlights•A comprehensive review of bicuspid valve disease, focusing on imaging and therapeutic options.•Detailed discussion of multimodality imaging for bicuspid aortic valve disease.•Approaches to surgery and transcatheter aortic valve replacement.•Discussion of available data and technical considerations.•Emphasis on multidisciplinary heart team evaluation at dedicated valve centers.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC11307905&blobtype=pdf
Volume Number	1
DOI	10.1016/j.jscai.2022.100506
PubMed Central reference number	PMC11307905
Issue Number	6
PubMed reference number	39132366
Journal	Journal of the Society for Cardiovascular Angiography & Interventions [J Soc Cardiovasc Angiogr Interv]
e-ISSN	27729303
Language	English
Publisher	Elsevier
Publisher Date	2022-10-11
Access Restriction	Open
Rights License	This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). © 2022 The Authors
Subject Keyword	bicuspid aortic valve severe aortic stenosis surgical aortic valve replacement transcatheter aortic valve replacement
Content Type	Text
Resource Type	Article
Subject	Cardiology and Cardiovascular Medicine