Ceria nanoparticles: biomedical applications and toxicity.

Content Provider	Europe PMC
Author	{"type":"author","Corr_email":["wangyizhou@zju.edu.cn"]} {"type":"author","Corr_email":["zhzhang0608@ytu.edu.cn"]}
Abstract	Ceria nanoparticles (CeO2 NPs) have become popular materials in biomedical and industrial fields due to their potential applications in anti-oxidation, cancer therapy, photocatalytic degradation of pollutants, sensors, etc. Many methods, including gas phase, solid phase, liquid phase, and the newly proposed green synthesis method, have been reported for the synthesis of CeO2 NPs. Due to the wide application of CeO2 NPs, concerns about their adverse impacts on human health have been raised. This review covers recent studies on the biomedical applications of CeO2 NPs, including their use in the treatment of various diseases (e.‍g., Alzheimer’s disease, ischemic stroke, retinal damage, chronic inflammation, and cancer). CeO2 NP toxicity is discussed in terms of the different systems of the human body (e.‍g., cytotoxicity, genotoxicity, respiratory toxicity, neurotoxicity, and hepatotoxicity). This comprehensive review covers both fundamental discoveries and exploratory progress in CeO2 NP research that may lead to practical developments in the future.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC11087188&blobtype=pdf
ISSN	16731581
Volume Number	25
PubMed Central reference number	PMC11087188
Issue Number	5
PubMed reference number	38725338
Journal	Journal of Zhejiang University. Science. B [J Zhejiang Univ Sci B]
e-ISSN	18621783
DOI	10.1631/jzus.b2300854
Language	English
Publisher	Zhejiang University Press
Publisher Date	2024-05-01
Publisher Place	China
Access Restriction	Open
Rights License	© Zhejiang University Press 2024
Subject Keyword	二氧化铈纳米颗粒 合成方法 生物医学应用程序 氧化应激 毒性 Ceria nanoparticle Synthetic method Biomedical application Oxidative stress Toxicity
Content Type	Text
Resource Type	Article
Subject	Veterinary Medicine Biochemistry, Genetics and Molecular Biology Pharmacology, Toxicology and Pharmaceutics