NDLI: Cardiac Amyloidosis: Clinical Features, Pathogenesis, Diagnosis, and Treatment.

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Cardiac Amyloidosis: Clinical Features, Pathogenesis, Diagnosis, and Treatment.

Content Provider	Europe PMC
Author	Argon, Asuman Nart, Deniz Yılmaz Barbet, Funda
Copyright Year	2024
Abstract	Cardiac amyloidosis is a type of amyloidosis that deserves special attention as organ involvement significantly worsens the prognosis. Cardiac amyloidosis can be grouped under three main headings: immunoglobulin light chain (AL) amyloidosis that is dependent on amyloidogenic monoclonal light chain production; hereditary Transthyretin (TTR) amyloidosis that results from accumulation of mutated TTR; and wild-type (non-hereditary) TTR amyloidosis formerly known as senile amyloidosis. Although all three types cause morbidity and mortality due to severe heart failure when untreated, they contain differences in their pathogenesis, clinical findings, and treatment. In this article, the clinical features, pathogenesis, diagnosis, and treatment methods of cardiac amyloidosis will be explained with an overview, and an awareness will be raised in the diagnosis of this disease.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC10823787&blobtype=pdf
ISSN	10185615
Volume Number	40
DOI	10.5146/tjpath.2023.12923
PubMed Central reference number	PMC10823787
Issue Number	1
PubMed reference number	38111336
Journal	Turkish Journal of Pathology [Turk Patoloji Derg]
e-ISSN	13095730
Language	English
Publisher	Federation of Turkish Pathology Societies
Publisher Date	2024-01-01
Publisher Place	Ankara, Turkey
Access Restriction	Open
Rights License	This is an open-access article published by Federation of Turkish Pathology Societies under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms. Copyright © 2024 The Author(s).
Subject Keyword	Amyloid Cardiac amyloidosis Transthyretin Hereditary amyloidosis Senile amyloidosis
Content Type	Text
Resource Type	Article
Subject	Pathology and Forensic Medicine

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