Magnitude of opportunistic infections and associated factors among adult people living with human immune deficient virus on art at selected public hospital, mogadishu somalia: cross-sectional study.

Content Provider	Europe PMC
Author	Mohamud, Abdirahman Khalif Ahmed, Omar Abdullahi Mohamud, Abdulrahman Ahmed Dirie, Najib Isse
Copyright Year	2023
Abstract	Introduction:Opportunistic infections (OIs) remain the leading cause of death among people living with Human immune deficient virus and OIs-related mortality in Africa is estimated at 310 000 cases. Besides, Somalia has scant data about OIs since a high burden of tuberculosis and HIV co-infection has been reported. Hence, up-to-date information is vital for better treatment and interventions and may support national and international HIV strategies and eradication programs. Therefore, this study aims to estimate the magnitude of OIs and determine factors associated with among people living with HIV/AIDs on anti-retroviral therapy (ART) in a selected public hospital in Mogadishu, Somalia.Materials and methods:A hospital-based cross-sectional study was conducted between 1 June and 30 August 2022 by interviewing HIV patients and reviewing case record files using a validated questionnaire containing sociodemographic, clinical, OIs history, behavioural and environmental characteristics. Logistic regression was used to determine factors associated with OIs at the significance level of a=0.05.Result:The magnitude of OIs among people living with HIV was 37.1% (95% CI=31.6–42.2); major identified OIs were pulmonary tuberculosis 8.2%, Diarrhoea 7.9%, and Pneumonia 4.3%. Based on Multivariable logistic regression drinking non-sterilized water [adjusted odds ratio (AOR)=2.395, 95% CI: 2.010–4.168], living with domestic animals (AOR=4.012, 95% CI: 1.651–4.123), Co-morbidity of chronic disease (AOR=2.910, 95% CI: 1.761–3.450), and poor ART adherence (AOR=3.121, 95% CI: 1.532–6.309) were factors associated with OIs.Conclusion:Human immune deficient virus patients in Mogadishu, Somalia, suffer from OIs. The OIs reduction strategies should improve drinking water sanitation, provide special consideration for those living with domestic animals and those with a co-morbid chronic disease, and improve ART adherence.
Volume Number	85
PubMed Central reference number	PMC10328614
Issue Number	7
PubMed reference number	37427157
Journal	Annals of Medicine and Surgery [Ann Med Surg (Lond)]
e-ISSN	20490801
DOI	10.1097/MS9.0000000000000880
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2023-06-06
Publisher Place	Hagerstown, MD
Access Restriction	Open
Rights License	This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.
Subject Keyword	factors associated HIV/AIDs mogadishu opportunistic infections prevalence somalia
Content Type	Text
Resource Type	Article
Subject	Surgery