Benefits of fermented synbiotic soymilk containing Lactobacillus acidophilus, Bifidobacterium lactis, and inulin towards lead toxicity alleviation.

Content Provider	Europe PMC
Author	Riasatian, Maryamsadat Mazloomi, Seyed Mohammad Ahmadi, Afsane Derakhshan, Zahra Rajabi, Saeed
Copyright Year	2023
Abstract	This study aims to evaluate the effect of fermented synbiotic soy milk containing Lactobacillus acidophilus, Bifidobacterium lactis, and inulin on a series of hematological and oxidative stress parameters, as well as serum lead levels in rats. In this study, 56 male Sprague-Dawley rats were randomly assigned to assess probiotics (L. acidophilus or B. lactis), probiotics with prebiotics (i.e., inulin), and the corresponding controls. Several hematologic parameters (red blood cell (RBC)), hematocrit (HCT) and hemoglobin (Hgb)), serum lead levels, superoxide dismutase (SOD) activity, and malondialdehyde (MDA) presence was measured to evaluate changes on day 42. Although a significant difference was observed in serum lead levels, there were no significant changes in hematological and oxidative stress parameters between the study groups. In conclusion, this study demonstrates that administering synbiotic fermented soy milk containing the probiotic Lactobacillus acidophilus and the prebiotic inulin may significantly improve serum lead levels in rats.
Journal	Heliyon
Volume Number	9
PubMed Central reference number	PMC10319184
Issue Number	6
PubMed reference number	37408889
e-ISSN	24058440
DOI	10.1016/j.heliyon.2023.e17518
Language	English
Publisher	Elsevier
Publisher Date	2023-06-23
Access Restriction	Open
Rights License	This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). © 2023 The Authors
Subject Keyword	Lead Soybean milk Probiotic bacteria Prebiotic Oxidative stress
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary