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Unravelling the genetic architecture of human complex traits through whole genome sequencing.
| Content Provider | Europe PMC |
|---|---|
| Author | Bocher, Ozvan Willer, Cristen J. Zeggini, Eleftheria |
| Abstract | Whole genome sequencing has enabled new insights into the genetic architecture of complex traits, especially through access to low-frequency and rare variation. This Comment highlights the key contributions from this technology and discusses considerations for its use and future perspectives. |
| Journal | Nature Communications [Nat Commun] |
| Volume Number | 14 |
| DOI | 10.1038/s41467-023-39259-x |
| PubMed Central reference number | PMC10267118 |
| Issue Number | 1 |
| PubMed reference number | 37316478 |
| e-ISSN | 20411723 |
| Language | English |
| Publisher | Nature Publishing Group |
| Publisher Date | 2023-06-14 |
| Publisher Place | London |
| Access Restriction | Open |
| Subject Keyword | Next-generation sequencing Genome-wide association studies Rare variants |
| Content Type | Text |
| Resource Type | Report |
| Subject | Chemistry Biochemistry, Genetics and Molecular Biology Physics and Astronomy |