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Transcriptional activation of endogenous Oct4 via the CRISPR/dCas9 activator ameliorates Hutchinson-Gilford progeria syndrome in mice.
| Content Provider | Europe PMC |
|---|---|
| Author | Kim, Junyeop Hwang, Yerim Kim, Sumin Chang, Yujung Kim, Yunkyung Kwon, Youngeun Kim, Jongpil |
| Page Count | 14 |
| ISSN | 14749718 |
| Journal | Aging Cell |
| Volume Number | 22 |
| PubMed Central reference number | PMC10265166 |
| Issue Number | 6 |
| PubMed reference number | 36964992 |
| e-ISSN | 14749726 |
| DOI | 10.1111/acel.13825 |
| Language | English |
| Publisher | John Wiley and Sons Inc. |
| Publisher Date | 2023-03-25 |
| Publisher Place | Hoboken |
| Access Restriction | Open |
| Rights License | This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2023 The Authors. Aging Cell published by Anatomical Society and John Wiley & Sons Ltd. |
| Subject Keyword | aging CRISPR/dCas9 Hutchinson‐Gilford progeria syndrome Oct4 rejuvenation |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Aging |