NDLI: The Impact and Effectiveness of Weight Loss on Kidney Transplant Outcomes: A Narrative Review.

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The Impact and Effectiveness of Weight Loss on Kidney Transplant Outcomes: A Narrative Review.

Content Provider	Europe PMC
Author	Sarno, Gerardo Frias-Toral, Evelyn Ceriani, Florencia Montalván, Martha Quintero, Beatriz Suárez, Rosario García Velasquèz, Eloísa Muscogiuri, Giovanna Iannelli, Antonio Pilone, Vincenzo Schiavo, Luigi
Editor	Shibagaki, Yugo
Copyright Year	2023
Abstract	Obesity is a worldwide epidemic that leads to several non-communicable illnesses, including chronic kidney disease (CKD). Diet and lifestyle modifications have shown a limited impact in the treatment of obesity. Because the group of end-stage renal disease (ESRD) patients examined in this study had limited access to kidney transplantation (KT), patients with obesity were thought to be at an increased risk of intraoperative and postoperative KT complications. Although bariatric surgery (BS) is now recognized as the gold standard treatment for morbid obesity, its role in ESRD or kidney transplant patients remains unknown. It is critical to know the correlation between weight loss and complications before and after KT, the impact of the overall graft, and patients’ survival. Hence, this narrative review aims to present updated reports addressing when to perform surgery (before or after a KT), which surgical procedure to perform, and again, if strategies to avoid weight regain must be specific for these patients. It also analyzes the metabolic alterations produced by BS and studies its cost-effectiveness pre- and post-transplantation. Due to the better outcomes found in KT recipients, the authors consider it more convenient to perform BS before KT. However, more multicenter trials are required to provide a solid foundation for these recommendations in ERSD patients with obesity.
Journal	Nutrients
Volume Number	15
PubMed Central reference number	PMC10255583
Issue Number	11
PubMed reference number	37299471
e-ISSN	20726643
DOI	10.3390/nu15112508
Language	English
Publisher	MDPI
Publisher Date	2023-05-28
Access Restriction	Open
Rights License	Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors.
Subject Keyword	obesity bariatric surgery chronic renal insufficiency chronic kidney failure kidney transplantation
Content Type	Text
Resource Type	Article
Subject	Food Science Nutrition and Dietetics

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