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Ductal Carcinoma in Situ: A Detailed Review of Current Practices.
| Content Provider | Europe PMC |
|---|---|
| Author | Kalwaniya, Dheer S Gairola, Madhur Gupta, Sumedha Pawan, G |
| Editor | Muacevic, Alexander Adler, John R |
| Copyright Year | 2023 |
| Abstract | Ductal carcinoma in situ is a challenge for breast surgeons, beginning with its difficult radiological detection and continuing with its contentious multimodal treatment and management. It is becoming more common as a result of widespread screening mammography and usually manifests as a cluster of calcifications. Patients are usually asymptomatic or present with a small, palpable lump. It is, however, a premalignant lesion that has the potential to progress to invasive carcinoma and is treated similarly with multimodal therapy. Treatment options currently include total or simple mastectomy with sentinel lymph node biopsy or lumpectomy with radiation. Tamoxifen and human epidermal growth factor receptor two suppression therapy are examples of adjuvant therapy. A review of consensus guidelines and literature was performed, in which we included the available online literature on the concerned topic from 2000-2022. This article is not a complete review of all the available literature; rather, it is a comprehensive review of the topic and its current management guidelines. |
| Journal | Cureus |
| Volume Number | 15 |
| DOI | 10.7759/cureus.37932 |
| PubMed Central reference number | PMC10200127 |
| Issue Number | 4 |
| PubMed reference number | 37220466 |
| e-ISSN | 21688184 |
| Language | English |
| Publisher | Cureus |
| Publisher Date | 2023-04-21 |
| Publisher Place | Palo Alto (CA) |
| Access Restriction | Open |
| Subject Keyword | dcis management risk factors for breast cancer ductal carcinoma in-situ dcis dcis prevalence |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |