Early Warning Systems for Emerging Profiles of Antimicrobial Resistance in Italy: A National Survey.

Content Provider	Europe PMC
Author	Iera, Jessica Seghieri, Chiara Tavoschi, Lara Isonne, Claudia Baccolini, Valentina Petrone, Daniele Agodi, Antonella Barchitta, Martina Arnoldo, Luca Creti, Roberta Forni, Silvia Raglio, Annibale Ricchizzi, Enrico Bandini, Lorenzo Grossi, Adriano D’Ancona, Fortunato
Editor	Veerapandian, Raja Joshi, Jagdish
Copyright Year	2023
Abstract	Antimicrobial resistance (AMR) national surveillance systems in Italy lack alert systems for timely detection of emerging profiles of AMR with potential relevance to public health. Furthermore, the existence of early warning systems (EWS) at subnational level is unclear. This study aims at mapping and characterizing EWS for microbiological threats available at regional level in Italy, focusing on emerging AMR, and at outlining potential barriers and facilitators to their development/implementation. To this end, a three-section, web-based survey was developed and administered to all Italian regional AMR representatives from June to August 2022. Twenty out of twenty-one regions and autonomous provinces (95.2%) responded to the survey. Among these, nine (45%) reported the implementation of EWS for microbiological threats at regional level, three (15%) reported that EWS are in the process of being developed, and eight (40%) reported that EWS are not currently available. EWS characteristics varied widely among the identified systems concerning both AMR profiles reported and data flow: the microorganisms most frequently included were extensively drug-resistant (XDR) Enterobacterales, with the lack of a dedicated regional IT platform reported in most cases. The results of this study depict a highly heterogeneous scenario and suggest that more efforts aimed at strengthening national AMR surveillance systems are needed.
ISSN	16617827
Journal	International Journal of Environmental Research and Public Health [Int J Environ Res Public Health]
Volume Number	20
DOI	10.3390/ijerph20095623
PubMed Central reference number	PMC10178630
Issue Number	9
PubMed reference number	37174143
e-ISSN	16604601
Language	English
Publisher	Molecular Diversity Preservation International (MDPI)
Publisher Date	2023-04-24
Access Restriction	Open
Subject Keyword	antimicrobial resistance early warning system emerging antimicrobial resistance surveillance
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Pollution Public Health, Environmental and Occupational Health