Effects of essential oil coated with glycerol monolaurate on growth performance, intestinal morphology, and serum profiles in weaned piglets.

Content Provider	Europe PMC
Author	Wang, Yanan Li, Juntao Wang, Huakai Mi, Yihai Xue, Yongqiang Li, Jiaan Ma, Yongxi
Copyright Year	2023
Abstract	ObjectiveThis study aimed to investigate the effects of essential oil coated with glycerol monolaurate (GML) on the growth performance, intestinal morphology, and serum profiles of weaned piglets.MethodsA total of 144 weaned piglets (Duroc×[Landrace×Yorkshire], average weight 8.07±3.33 kg) were randomly assigned to three groups with six replicate pens and eight piglets per pen: i) CON: a corn-soybean basal diet; ii) LEG: with 1,000 mg/kg essential oil coated with GML; and iii) HEG: with 2,000 mg/kg essential oil coated with GML.ResultsResults showed that average daily gain was increased (p<0.05) linearly by essential oil coated with GML supplementation on day 14 to 28 and day 0 to 28 compared with the CON group. Dietary supplementation with HEG increased (p<0.05) total antioxidant capacity and catalase activity on day 14, and immunoglobulin A (IgA) and IgM concentration on day 28 and tended to increase IgG on day 28. In addition, the crypt depth in the jejunum was reduced (p<0.05), and villus height and villus height/crypt depth in the ileum were increased (p<0.05) in the HEG group compared with the CON group. Moreover, lower (p<0.05) concentrations of tumor necrosis factor-α, interferon-γ, interleukin-1β (IL-1β), IL-8, and IL-10 were observed in the jejunum of piglets supplemented with HEG compared with the CON group. In addition, dietary HEG tended to decrease IL-6 level in the jejunum of piglets compared with the CON group.ConclusionDietary essential oil coated with GML can improve growth performance of weaned piglets. Moreover, supplementing 2,000 mg/kg essential oil coated with GML was demonstrated to improve antioxidant ability, and intestinal morphology, and reduce jejunal inflammatory factor levels.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC10164486&blobtype=pdf
ISSN	27650189
Journal	Animal Bioscience [Anim Biosci]
Volume Number	36
DOI	10.5713/ab.22.0261
PubMed Central reference number	PMC10164486
Issue Number	5
PubMed reference number	36397690
e-ISSN	27650235
Language	English
Publisher	Animal Bioscience
Publisher Date	2022-11-14
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Subject Keyword	Antioxidant Capacity Essential Oil Glycerol Monolaurate Immunity Function Piglets
Content Type	Text
Resource Type	Article
Subject	Genetics Physiology Veterinary Animal Science and Zoology Food Science