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Strategies for Surface Design in Surface Plasmon Resonance (SPR) Sensing.
| Content Provider | Europe PMC |
|---|---|
| Author | Topor, Cristina-Virginia Puiu, Mihaela Bala, Camelia |
| Copyright Year | 2023 |
| Abstract | Surface plasmon resonance (SPR) comprises several surface-sensitive techniques that enable the trace and ultra-trace detection of various analytes through affinity pairing. Although enabling label-free, sensitive detection and real-time monitoring, several issues remain to be addressed, such as poor stability, non-specific adsorption and the loss of operational activity of biomolecules. In this review, the progress over sensor modification, immobilization techniques and novel 2D nanomaterials, gold nanostructures and magnetic nanoparticles for signal amplification is discussed. The advantages and disadvantages of each design strategy will be provided together with some of the recent achievements. |
| Volume Number | 13 |
| PubMed Central reference number | PMC10136606 |
| Issue Number | 4 |
| PubMed reference number | 37185540 |
| Journal | Biosensors (Basel) |
| e-ISSN | 20796374 |
| DOI | 10.3390/bios13040465 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2023-04-07 |
| Access Restriction | Open |
| Rights License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors. |
| Subject Keyword | biosensor surface plasmon resonance immobilization click chemistry nanomaterials metal organic framework |
| Content Type | Text |
| Resource Type | Article |
| Subject | Clinical Biochemistry Instrumentation Medicine Biomedical Engineering Engineering Analytical Chemistry Biotechnology |
