Influence of Disease Acceptance on the Quality of Life of Patients with Ankylosing Spondylitis - Single Centre Study.

Content Provider	Europe PMC
Author	Wysocki, Grzegorz Czapla, Michał Uchmanowicz, Bartosz Fehler, Piotr Aleksandrowicz, Katarzyna Rypicz, Łukasz Wolska-Zogata, Irena Uchmanowicz, Izabella
Copyright Year	2023
Abstract	IntroductionAnkylosing spondylitis (AS) is a chronic, progressive disease, often with multiple complications, with periods of exacerbation and remission. The onset of the disease usually affects people under 30 years of age. The disease impairs physical, psychological, and social functioning, leading to disability. Therefore, patients with AS face the challenge of adapting to life with the condition and deteriorating quality of life (QoL).ObjectiveThis study aimed to assess the impact of disease acceptance on quality of life in patients with AS.Material and MethodsThe study was conducted in the Department of Rheumatology and Internal Diseases of the University Hospital in Wrocław among 110 patients (67 men and 43 women) with the diagnosis of AS, aged 20–89 years (M=48.44 years, SD±12.55). The study used the Acceptance of Illness Scale (AIS), the WHOQoL-BREF Quality of Life Scale, and a self-constructed questionnaire of clinical and sociodemographic data.ResultsRespondents rated the quality of life as good and moderate (M = 3.49 points, SD=±0.84). The mean AIS score was 27.44 (SD=±8.67). AIS scores are positively correlated with all QoL domains and perception of quality of life and health (p<0.001). The strongest correlation was in the physical domain (r=0.71), while the weakest correlation was observed in the social domain (r=0.329). AIS and QoL measures showed significant relationships with selected sociodemographic data (eg, gender, age, education, and occupational activity) and correlated with selected disease data (eg, type of treatment used, duration of disease, or comorbidities).ConclusionAIS in patients with AS condition correlated positively with their QoL in all domains. Both disease acceptance and quality of life are influenced by specific sociodemographic and disease-related data. Prevention of complications and the type of treatment for AS (primarily biological treatment) can be essential in improving patients’ quality of life.
Page Count	18
Journal	Patient preference and adherence
Volume Number	17
PubMed Central reference number	PMC10119491
PubMed reference number	37090183
e-ISSN	1177889X
DOI	10.2147/PPA.S403437
Language	English
Publisher	Dove
Publisher Date	2023-04-18
Access Restriction	Open
Rights License	This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). © 2023 Wysocki et al.
Subject Keyword	ankylosing spondylitis health-related quality of life quality of life acceptance of illness
Content Type	Text
Resource Type	Article
Subject	Pharmacology, Toxicology and Pharmaceutics Social Sciences Health Policy Medicine