NDLI: White Adipose Tissue Dysfunction: Pathophysiology and Emergent Measurements.

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White Adipose Tissue Dysfunction: Pathophysiology and Emergent Measurements.

Content Provider	Europe PMC
Author	Santillana, Natalia Astudillo-Guerrero, Camila D’Espessailles, Amanda Cruz, Gonzalo
Editor	Gómez-Ambrosi, Javier Fernández-López, José Antonio
Copyright Year	2023
Abstract	White adipose tissue (AT) dysfunction plays an important role in the development of cardiometabolic alterations associated with obesity. AT dysfunction is characterized by the loss of the expansion capacity of the AT, an increment in adipocyte hypertrophy, and changes in the secretion profile of adipose cells, associated with accumulation of macrophages and inflammation. Since not all people with an excess of adiposity develop comorbidities, it is necessary to find simple tools that can evidence AT dysfunction and allow the detection of those people with the potential to develop metabolic alterations. This review focuses on the current pathophysiological mechanisms of white AT dysfunction and emerging measurements to assess its functionality.
Journal	Nutrients
Volume Number	15
PubMed Central reference number	PMC10096946
Issue Number	7
PubMed reference number	37049561
e-ISSN	20726643
DOI	10.3390/nu15071722
Language	English
Publisher	MDPI
Publisher Date	2023-03-31
Access Restriction	Open
Rights License	Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors.
Subject Keyword	adipose tissue dysfunction inflammation obesity visceral fat fibrosis
Content Type	Text
Resource Type	Article
Subject	Food Science Nutrition and Dietetics

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