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Comparison of Ultrasound Scores in Differentiating between Benign and Malignant Adnexal Masses.
| Content Provider | Europe PMC |
|---|---|
| Author | Pelayo, Mar Pelayo-Delgado, Irene Sancho-Sauco, Javier Sanchez-Zurdo, Javier Abarca-Martinez, Leopoldo Corraliza-Galán, Virginia Martin-Gromaz, Carmen Pablos-Antona, María Jesús Zurita-Calvo, Julia Alcázar, Juan Luis |
| Editor | Tse, Ka Yu Chu, Mandy |
| Copyright Year | 2023 |
| Abstract | Subjective ultrasound assessment by an expert examiner is meant to be the best option for the differentiation between benign and malignant adnexal masses. Different ultrasound scores can help in the classification, but whether one of them is significantly better than others is still a matter of debate. The main aim of this work is to compare the diagnostic performance of some of these scores in the evaluation of adnexal masses in the same set of patients. This is a retrospective study of a consecutive series of women diagnosed as having a persistent adnexal mass and managed surgically. Ultrasound characteristics were analyzed according to IOTA criteria. Masses were classified according to the subjective impression of the sonographer and other ultrasound scores (IOTA simple rules -SR-, IOTA simple rules risk assessment -SRRA-, O-RADS classification, and ADNEX model -with and without CA125 value-). A total of 122 women were included. Sixty-two women were postmenopausal (50.8%). Eighty-one women had a benign mass (66.4%), and 41 (33.6%) had a malignant tumor. The sensitivity of subjective assessment, IOTA SR, IOTA SRRA, and ADNEX model with or without CA125 and O-RADS was 87.8%, 66.7%, 78.1%, 95.1%, 87.8%, and 90.2%, respectively. The specificity for these approaches was 69.1%, 89.2%, 72.8%, 74.1%, 67.9%, and 60.5%, respectively. All methods with similar AUC (0.81, 0.78, 0.80, 0.88, 0.84, and 0.75, respectively). We concluded that IOTA SR, IOTA SRRA, and ADNEX models with or without CA125 and O-RADS can help in the differentiation of benign and malignant masses, and their performance is similar to the subjective assessment of an experienced sonographer. |
| Journal | Diagnostics (Basel, Switzerland) |
| Volume Number | 13 |
| PubMed Central reference number | PMC10093240 |
| Issue Number | 7 |
| PubMed reference number | 37046525 |
| e-ISSN | 20754418 |
| DOI | 10.3390/diagnostics13071307 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2023-03-30 |
| Access Restriction | Open |
| Rights License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors. |
| Subject Keyword | transvaginal ultrasound adnexal masses IOTA simple rules IOTA simple rules risk assessment O-RADS ADNEX model CA125 diagnosis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Clinical Biochemistry |
