Safety of Continuing Aspirin Use in Cervical Laminoplasty: A Propensity Score-Matched Analysis.

Content Provider	Europe PMC
Author	Chung Wong, Yu Kit Lau, Tsun Wang Chau, Wai On Kwok, Kin Wai Law, Sheung
Abstract	Introduction Aspirin is commonly used for the primary and secondary prevention of cardiovascular disease and stroke. Controversy exists concerning whether and when is the optimal time to stop aspirin before spinal surgery. Previous studies on this topic mainly focused on patients who received thoracolumbar spine surgeries. There are only a few literatures concerning the safety of aspirin use in cervical spine surgery patients. Methods This pilot study recruited patients who received cervical laminoplasty from January 2010 to December 2021. The operation time, intraoperative blood loss, and postoperative complications of the patients who had taken aspirin during the perioperative period were compared with age, sex, and comorbidity-matched control patients. Propensity score matching was utilized in the selection of control to minimize bias. Results Twenty-one patients who have received cervical laminoplasty while taking aspirin during the perioperative period were included. The control group included 21 age, sex, and comorbidity-matched patients who have not taken aspirin. The operation time and intraoperative and postoperative blood loss were higher in patients taking aspirin but were not statistically significant. There was no statistically significant difference in the wound infection rate. No case of epidural hematoma was found. Conclusions In patients undergoing cervical laminoplasty, a continuation of aspirin is safe and does not increase the difficulty of the surgery, wound complication, or hemorrhage.
Related Links	https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC10083087&blobtype=pdf
Journal	Spine Surgery and Related Research [Spine Surg Relat Res]
Volume Number	7
DOI	10.22603/ssrr.2022-0163
PubMed Central reference number	PMC10083087
Issue Number	2
PubMed reference number	37041877
e-ISSN	2432261X
Language	English
Publisher	The Japanese Society for Spine Surgery and Related Research
Publisher Date	2022-10-28
Access Restriction	Open
Rights License	Spine Surgery and Related Research is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). Copyright © 2023 The Japanese Society for Spine Surgery and Related Research
Subject Keyword	Aspirin cervical spine surgery laminoplasty complications blood loss
Content Type	Text
Resource Type	Article
Subject	Neurology (clinical) Orthopedics and Sports Medicine Surgery