Research Progress on Chemical Constituents and Pharmacological Activities of Menispermi Rhizoma.

Content Provider	Europe PMC
Author	Zhai, Xuan Wang, Kangmin Gao, Xingyi Yan, Bin
Editor	Ferrante, Claudio
Copyright Year	2023
Abstract	Menispermi Rhizoma, the rhizome of Menispermum dauricum DC., is a traditional Chinese medicine, which has the effect of clearing away heat and detoxification, dispelling wind, and relieving pain. It is often used in the treatment of sore throat, enteritis, dysentery, and rheumatism. The chemical constituents of M. Rhizoma mainly include alkaloids, phenolic acids, quinones, cardiotonic glycosides, and so on. Modern pharmacological studies have proved that M. Rhizoma has the effects of anti-tumour, anti-inflammation, anti-oxidation, bacteriostasis, cardio-cerebrovascular protection, anti-depression and anti-Alzheimer's disease. In recent years, the chemical constituents of M. Rhizoma have been found continuously, and the pharmacological studies have deepened gradually. This paper reviews the research progress on the chemical composition and pharmacological effects of M. Rhizoma, to provide a basis for further research and development of its medicinal value.
Journal	Molecules
Volume Number	28
DOI	10.3390/molecules28062701
PubMed Central reference number	PMC10054850
Issue Number	6
PubMed reference number	36985672
e-ISSN	14203049
Language	English
Publisher	Molecular Diversity Preservation International (MDPI)
Publisher Date	2023-03-16
Access Restriction	Open
Subject Keyword	Menispermi Rhizoma chemical constituents pharmacological activities research progress
Content Type	Text
Resource Type	Article
Subject	Physical and Theoretical Chemistry Medicine Chemistry Drug Discovery Pharmaceutical Science Analytical Chemistry Molecular Medicine Organic Chemistry