Retinal Vessel Local Tortuosity under a Macula-to-Optic Disc Central-Framing Change.

Content Provider	Europe PMC
Author	Ramírez, Natalia Ralló, Miquel Millan, Maria S.
Editor	Łabuz, Grzegorz
Copyright Year	2023
Abstract	Some ocular and cardiovascular diseases can be detected through the increased tortuosity of retinal blood vessels. Objective tortuosity measures can be obtained from digital image analysis of a retinography. This study tested a set of local tortuosity indices under a change in the frame center (macula, optic disc) of the eye fundus image. We illustrate the effects of such a change on 40 pairs of vessels evaluated with eight tortuosity indices. We show that the frame center change caused significant differences in the mean values of the vast majority of the tortuosity indices analyzed. The index defined as the ratio of the curvature to the arc length of a vessel segment proved to be the most robust in relation to a frame center change. Experimental results obtained from the analysis of clinical images are provided and discussed.
Journal	Diagnostics (Basel, Switzerland)
Volume Number	13
PubMed Central reference number	PMC10046985
Issue Number	6
PubMed reference number	36980338
e-ISSN	20754418
DOI	10.3390/diagnostics13061030
Language	English
Publisher	MDPI
Publisher Date	2023-03-08
Access Restriction	Open
Rights License	Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). © 2023 by the authors.
Subject Keyword	tortuosity index retinography vessel segmentation digital eye fundus image
Content Type	Text
Resource Type	Article
Subject	Clinical Biochemistry