New Fluorescent Nanosensor for Determination of Diazepam Using Molecularly Imprinted Mn-doped ZnS Quantum Dots.

Content Provider	Europe PMC
Author	Samadi-Maybodi, Abdolraouf Abbasifar, Javad Malekaneh, Mohammad
Copyright Year	2022
Abstract	In this study, molecularly imprinted Mn-doped ZnS quantum dots were used as nanosensors to determine diazepam and its metabolites. Mn-doped ZnS quantum dots (QDs) capped with L-cysteine were prepared using a sodium thiosulfate precursor and characterized by various methods. Methacrylic acid was used as a precursor for the synthesis of MIP Mn-doped ZnS QDs and then used to measure diazepam in various samples. The linear dynamic range, coefficient of determination, and detection limit were found to be 0.3 - 250 µmol/L, 0.989 and 8.78 × 10-2 µmol/L, respectively. The interference studies showed that the prepared nanosensor was selective for diazepam and its metabolites
ISSN	17350328
Journal	Iranian Journal of Pharmaceutical Research : IJPR
Volume Number	21
PubMed Central reference number	PMC10024321
Issue Number	1
PubMed reference number	36942073
e-ISSN	17266890
DOI	10.5812/ijpr-127351
Language	English
Publisher	Brieflands
Publisher Date	2022-09-05
Access Restriction	Open
Rights License	This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. Copyright © 2022, Author(s)
Subject Keyword	Diazepam Molecularly Imprinted Polymers Mn-doped ZnS Polymethacrylic Acid Quantum Dots
Content Type	Text
Resource Type	Article
Subject	Pharmacology, Toxicology and Pharmaceutics Pharmacology (medical)