Loading...
Please wait, while we are loading the content...
Similar Documents
Characterizing a lethal mitonuclear incompatibility in naturally hybridizing Xiphophorus swordtails (Dataset)
| Content Provider | Dryad |
|---|---|
| Author | Moran, Benjamin Payne, Cheyenne Powell, Daniel Iverson, Erik Donny, Alex Banerjee, Shreya Langdon, Quinn Gunn, Theresa Rodriguez-Soto, Rebecca Madero, Angel Baczenas, John Kleczko, Korbin Liu, Fang Matney, Rowan Singhal, Kratika Leib, Ryan Hernandez-Perez, Osvaldo Corbett-Detig, Russell Frydman, Judith Gifford, Casey Schartl, Manfred Havird, Justin Schumer, Molly |
| Abstract | The evolution of reproductive barriers is the first step in the formation of new species and can help us understand the diversification of life on Earth. These reproductive barriers often take the form of “hybrid incompatibilities,” where alleles derived from two different species no longer interact properly in hybrids. Theory predicts that hybrid incompatibilities may be more likely to arise at rapidly evolving genes and that incompatibilities involving multiple genes should be common, but there has been sparse empirical data to evaluate these predictions. Here, we describe a mitonuclear incompatibility involving three genes in physical contact within respiratory Complex I of naturally hybridizing swordtail fish species. Individuals homozygous for mismatched protein combinations fail to complete embryonic development or die as juveniles, while those heterozygous for the incompatibility have reduced Complex I function and unbalanced representation of parental alleles in the mitochondrial proteome. We find that the impacts of different genetic interactions on survival are non-additive, highlighting subtle complexity in the genetic architecture of hybrid incompatibilities. Finally, we document the evolutionary history of the genes involved, showing signals of accelerated evolution and the first case of an incompatibility transferred between species via hybridization. |
| File Size | 15122192581 |
| File Format | HTM / HTML |
| ISSN | 00280836 |
| DOI | 10.5061/dryad.j3tx95xmx |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701668 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701669 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701667 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701666 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701670 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701671 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701688 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701673 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701672 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701686 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701687 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701674 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701675 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701685 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701676 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701677 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701679 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701678 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701684 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701691 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701680 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701681 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701682 |
| Alternate Webpage(s) | https://datadryad.org/stash/downloads/file_stream/2701683 |
| Language | English |
| Publisher Date | 2023-11-20 |
| Access Restriction | Open |
| Subject Keyword | Xiphophorus Malinche Birchmanni Cortezi Respirometry Mitochondrial Genetics Oxidative Phosphorylation Protein Structure Proteomics Gene Mapping Epistasis Evolutionary Rate Coevolution Histology Flow Cytometry Sequence Alignment |
| Content Type | Text |
| Resource Type | Data Set |
| Subject | Multidisciplinary |
