NDLI: Synthesis, spectroscopic characterization and in vitro antimicrobial studies of Schiff base ligand, H2L derived from glyoxalic acid and 1,8-diaminonaphthalene and its Co(II), Ni(II), Cu(II) and Zn(II) complexes

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Synthesis, spectroscopic characterization and in vitro antimicrobial studies of Schiff base ligand, H2L derived from glyoxalic acid and 1,8-diaminonaphthalene and its Co(II), Ni(II), Cu(II) and Zn(II) complexes

Content Provider	Directory of Open Access Journals (DOAJ)
Author	Nida Shahid Mohammad Azam Asad U. Khan Mohammad Shakir Saud I. Al-Resayes
Abstract	A novel Schiff base ligand, N,N′-bis (glyoxalicacidcarboxaldiimine)-1,8-diaminonaphthalene [H2L] obtained by the condensation of glyoxalic acid and 1,8-diaminonaphthalene and its mononuclear complexes of type, [ML] [M = Co(II), Ni(II), Cu(II), Zn(II)] have been synthesized and characterized on the basis of elemental analysis, molar conductance, magnetic susceptibility measurements and spectroscopic studies viz., FT-IR, EPR, 1H NMR, FAB-Mass, UV–vis and magnetic moment data. A square planar geometry has been assigned on the basis of UV–vis and magnetic susceptibility around Co(II), Ni(II) and Cu(II) ions while conductivity data showed non electrolytic nature of all the complexes. The synthesized ligand, H2L and its complexes have been tested against Streptococcus mutans, Staphylococcus pyogenes, MRSA (Gram positive bacteria), Pseudomonas aeruginosa, Salmonella typhimurium, Escherichia coli (Gram negative bacteria), Candida albicans, Candida krusei, Candida parapsilosis and Candida neroformans and results suggested that Cu(II) complex has significant antimicrobial activity.
Related Links	http://www.sciencedirect.com/science/article/pii/S1878535211002899
ISSN	18785352
DOI	10.1016/j.arabjc.2011.11.004
Journal	Arabian Journal of Chemistry
Issue Number	3
Volume Number	9
Language	English
Publisher	Elsevier
Publisher Date	2016-01-01
Publisher Place	Netherlands
Access Restriction	Open
Subject Keyword	Chemistry Schiff Base 1,8-diaminonaphthalene Spectroscopic Studies Antimicrobial Activity
Content Type	Text
Resource Type	Article
Subject	Chemistry Chemical Engineering

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