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Asymmetric catalytic hydrogenation of imines and enamines in natural product synthesis
| Content Provider | Directory of Open Access Journals (DOAJ) |
|---|---|
| Author | Pei Tang Huijing Wang Wen Zhang Fen-Er Chen |
| Abstract | Asymmetric catalytic hydrogenations of imines and enamines with chiral transition-metal complexes bearing chiral ligands are among the most green and powerful approaches for the elaboration of chiral amine structures in organic synthesis. This review focuses on recent applications of asymmetric hydrogenations of imine and enamine substrates in the total syntheses of natural products. These applications include diverse processes involving asymmetric transfer hydrogenation (ATH) and asymmetric hydrogenation (AH) to form key chiral amine motifs in natural products with good efficiency and high-level enantiocontrol. |
| Related Links | http://www.sciencedirect.com/science/article/pii/S2666554920300065 |
| DOI | 10.1016/j.gresc.2020.05.006 |
| Journal | Green Synthesis and Catalysis |
| Issue Number | 1 |
| Volume Number | 1 |
| e-ISSN | 26665549 |
| Language | English |
| Publisher | KeAi Communications Co. Ltd. |
| Publisher Date | 2020-01-01 |
| Publisher Place | China |
| Access Restriction | Open |
| Subject Keyword | Chemical Technology Biochemistry Asymmetric Catalytic Hydrogenation Imine Substrates Enamine Substrates Natural Product Synthesis Enantioselectivity Chemical technology Technology Chemistry |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biotechnology Catalysis |