Ethyl 3-amino-2-carbamoyl-4-(4-methoxyphenyl)-6-methylthieno[2,3-b]pyridine-5-carboxylate dimethyl sulfoxide monosolvate

Content Provider	Directory of Open Access Journals (DOAJ)
Author	Etify A. Bakhite Manpreet Kaur Shaaban K. Mohamed Mehmet Akkurt Jerry P. Jasinski Mustafa R. Albayati
Abstract	The conformation of the title molecule, C19H19N3O4S·C2H6OS, which crystallized as a DMSO solvate, is partially determined by an intramolecular N—H...O hydrogen bond, forming an S(6) loop. The thienopyridine bicyclic system is almost planar, with an r.m.s. deviation of 0.002 Å. The benzene ring makes a dihedral angle of 65.44 (8)° with the mean plane of the thienopyridine bicyclic system. In the crystal, molecules are linked by pairs of N—H...O hydrogen bonds, forming inversion dimers with an R22(8) ring motif. Within the dimers, which stack along the a-axis direction, there is a weak π–π interaction [centroid-to-centroid distance = 3.5428 (11) Å] involving inversion-related thiophene rings. In addition, N—H...O and C—H...O hydrogen bonds help to consolidate the packing, via the solvent molecules.
Related Links	http://scripts.iucr.org/cgi-bin/paper?S2414314616014747
ISSN	24143146
DOI	10.1107/S2414314616014747
Journal	IUCrData
Issue Number	9
Volume Number	1
Language	English
Publisher	International Union of Crystallography
Publisher Date	2016-01-01
Publisher Place	United Kingdom
Access Restriction	Open
Subject Keyword	Crystallography Crystal Structure Dimethyl Sulfoxide Thienopyridine Derivative
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Analytical Chemistry Inorganic Chemistry