NDLI: In vivo determination of mouse olfactory mucus cation concentrations in normal and inflammatory states.

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Yeasts acquire resistance secondary to antifungal drug treatment by adaptive mutagenesis.

The transcription factor NFATp plays a key role in susceptibility to TB in mice.

Measuring health-related quality of life of HIV-positive adolescents in resource-constrained settings.

Sequencing intractable DNA to close microbial genomes.

Gemcitabine and irinotecan as first-line therapy for carcinoma of unknown primary: results of a multicenter phase II trial.

Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation.

Fungal diversity associated with Hawaiian Drosophila host plants.

Neuroligin-1 loss is associated with reduced tenacity of excitatory synapses.

Correction: Research on the Stability of a Rabbit Dry Eye Model Induced by Topical Application of the Preservative Benzalkonium Chloride

Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells.

Is Fitts' law continuous in discrete aiming?

IFN-γ signaling to astrocytes protects from autoimmune mediated neurological disability.

Socioeconomic factors influencing hospitalized patients with pneumonia due to influenza A(H1N1)pdm09 in Mexico.

Haste makes waste but condition matters: molt rate-feather quality trade-off in a sedentary songbird.

Factors associated with delays in treatment initiation after tuberculosis diagnosis in two districts of India.

Is the association between general cognitive ability and violent crime caused by family-level confounders?

Conserved synthetic peptides from the hemagglutinin of influenza viruses induce broad humoral and T-cell responses in a pig model.

Structural interaction and functional regulation of polycystin-2 by filamin.

Female rose bitterling prefer MHC-dissimilar males: experimental evidence.

Aldolase B knockdown prevents high glucose-induced methylglyoxal overproduction and cellular dysfunction in endothelial cells.

Lichtheimia species exhibit differences in virulence potential.

Weed risk assessment for aquatic plants: modification of a New Zealand system for the United States.

Correction: Molecular Epidemiology of Neisseria meningitidis Serogroup B in Brazil

A new Cre driver mouse line, Tcf21/Pod1-Cre, targets metanephric mesenchyme.

Personal decision-making criteria related to seasonal and pandemic A(H1N1) influenza-vaccination acceptance among French healthcare workers.

BmK-YA, an enkephalin-like peptide in scorpion venom.

Multivariate analyses to assess the effects of surgeon and hospital volume on cancer survival rates: a nationwide population-based study in Taiwan.

Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies.

Shared human-chimpanzee pattern of perinatal femoral shaft morphology and its implications for the evolution of hominin locomotor adaptations.

Identification of a novel calcium binding motif based on the detection of sequence insertions in the animal peroxidase domain of bacterial proteins.

QuantiFERON®-TB gold in-tube performance for diagnosing active tuberculosis in children and adults in a high burden setting.

miRNA signature and Dicer requirement during human endometrial stromal decidualization in vitro.

Crystal structure of a monomeric thiolase-like protein type 1 (TLP1) from Mycobacterium smegmatis.

Inferring reputation promotes the evolution of cooperation in spatial social dilemma games.

DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression.

IL-15 expression on RA synovial fibroblasts promotes B cell survival.

Teamwork: improved eQTL mapping using combinations of machine learning methods.

Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia.

Using DNA barcoding to assess Caribbean reef fish biodiversity: expanding taxonomic and geographic coverage.

Always look on both sides: phylogenetic information conveyed by simple sequence repeat allele sequences.

Pelvis morphology, trunk posture and standing imbalance and their relations to the Cobb angle in moderate and severe untreated AIS.

Estrogen mediates innate and adaptive immune alterations to influenza infection in pregnant mice.

A new module in neural differentiation control: two microRNAs upregulated by retinoic acid, miR-9 and -103, target the differentiation inhibitor ID2.

Obesity or overweight is associated with worse pathological response to neoadjuvant chemotherapy among Chinese women with breast cancer.

Bayesian calibration of simultaneity in audiovisual temporal order judgments.

The "most wanted" taxa from the human microbiome for whole genome sequencing.

Plant innate immunity induced by flagellin suppresses the hypersensitive response in non-host plants elicited by Pseudomonas syringae pv. averrhoi.

Correction: Fact or Factitious? A Psychobiological Study of Authentic and Simulated Dissociative Identity States.

Hypercholesterolemia is associated with the apolipoprotein C-III (APOC3) genotype in children receiving HAART: an eight-year retrospective study.

Ocean acidification refugia of the Florida Reef Tract.

Correction: Research on the Stability of a Rabbit Dry Eye Model Induced by Topical Application of the Preservative Benzalkonium Chloride.

Biotinidase is a novel marker for papillary thyroid cancer aggressiveness.

Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule.

The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning.

The frames of reference of the motor-visual aftereffect.

Clinical significance of soluble hemoglobin scavenger receptor CD163 (sCD163) in sepsis, a prospective study.

Acute coronary syndrome in patients with prior coronary artery bypass surgery: observations from a 20-year registry in a middle-eastern country.

Impact of malaria on hematological parameters in people living with HIV/AIDS attending the Laquintinie Hospital in Douala, Cameroon.

A trans-Amazonian screening of mtDNA reveals deep intraspecific divergence in forest birds and suggests a vast underestimation of species diversity.

Structure-function relationships of the Mycobacterium tuberculosis transcription factor WhiB1.

Cell surface estrogen receptor alpha is upregulated during subchronic metabolic stress and inhibits neuronal cell degeneration.

NR4A1 (Nur77) mediates thyrotropin-releasing hormone-induced stimulation of transcription of the thyrotropin β gene: analysis of TRH knockout mice.

Blockage of spontaneous Ca2+ oscillation causes cell death in intraerythrocitic Plasmodium falciparum.

The association of 25-hydroxyvitamin D3 and D2 with behavioural problems in childhood.

Antagonism pattern detection between microRNA and target expression in Ewing's sarcoma.

Pyridoxal 5'-phosphate is a slow tight binding inhibitor of E. coli pyridoxal kinase.

Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin.

Cre-mediated stress affects sirtuin expression levels, peroxisome biogenesis and metabolism, antioxidant and proinflammatory signaling pathways.

Monocyte chemoattractant protein-1 secreted by decidual stromal cells inhibits NK cells cytotoxicity by up-regulating expression of SOCS3.

Correction: Molecular Characterisation of Transport Mechanisms at the Developing Mouse Blood–CSF Interface: A Transcriptome Approach

Iontophoresis of endothelin receptor antagonists in rats and men.

Birth weight, breast cancer and the potential mediating hormonal environment.

The structure and usage of female and male mouse ultrasonic vocalizations reveal only minor differences.

Phage morphology recapitulates phylogeny: the comparative genomics of a new group of myoviruses.

NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1.

Burkholderia cenocepacia type VI secretion system mediates escape of type II secreted proteins into the cytoplasm of infected macrophages.

Electroacupuncture decreases excessive alcohol consumption involving reduction of FosB/ΔFosB levels in reward-related brain regions.

Association of high blood pressure with renal insufficiency: role of albuminuria, from NHANES, 1999-2006.

Comparative expression profiling of distinct T cell subsets undergoing oxidative stress.

Gene expression profiling of dendritic cells in different physiological stages under Cordyceps sinensis treatment.

Moth sex pheromone receptors and deceitful parapheromones.

MassTRIX reloaded: combined analysis and visualization of transcriptome and metabolome data.

Characteristic features of kynurenine aminotransferase allosterically regulated by (alpha)-ketoglutarate in cooperation with kynurenine.

Risk factors for preterm birth in an international prospective cohort of nulliparous women.

Comparing the effect of naturally restored forest and grassland on carbon sequestration and its vertical distribution in the Chinese Loess Plateau.

Desert springs: deep phylogeographic structure in an ancient endemic crustacean (Phreatomerus latipes).

Humans running in place on water at simulated reduced gravity.

Effects of long and short carboxylated or aminated multiwalled carbon nanotubes on blood coagulation.

Correction: Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance.

Overexpression of TGF-ß1 in macrophages reduces and stabilizes atherosclerotic plaques in ApoE-deficient mice.

The hard problem of cooperation.

Insight into temperature dependence of GTPase activity in human guanylate binding protein-1.

A metric of influential spreading during contagion dynamics through the air transportation network.

Hemoglobin interactions with αB crystallin: a direct test of sensitivity to protein instability.

Biochemical and molecular characterization of the gentisate transporter GenK in Corynebacterium glutamicum.

Selective endothelial overexpression of arginase II induces endothelial dysfunction and hypertension and enhances atherosclerosis in mice.

Magnetic catechol-chitosan with bioinspired adhesive surface: preparation and immobilization of ω-transaminase.

Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck.

Singlet oxygen reactions with flavonoids. A theoretical-experimental study.

A reverse time-course method for transcriptional chase analyses of mRNA half-lives in cultured cells.

To eat or not to eat? Debris selectivity by marine turtles.

Hepatitis B and C co-infection are independent predictors of progressive kidney disease in HIV-positive, antiretroviral-treated adults.

An Asian validation of the TIMI risk score for ST-segment elevation myocardial infarction.

Impact of perinatal dioxin exposure on infant growth: a cross-sectional and longitudinal studies in dioxin-contaminated areas in Vietnam.

The effect of systematic clinical interventions with cigarette smokers on quit status and the rates of smoking-related primary care office visits.

Direct fitness correlates and thermal consequences of facultative aggregation in a desert lizard.

RhoC impacts the metastatic potential and abundance of breast cancer stem cells.

Wind and wildlife in the Northern Great Plains: identifying low-impact areas for wind development.

Minocycline inhibits alkali burn-induced corneal neovascularization in mice.

Vitamin E isoforms differentially regulate intercellular adhesion molecule-1 activation of PKCα in human microvascular endothelial cells.

Home-based aerobic interval training improves peak oxygen uptake equal to residential cardiac rehabilitation: a randomized, controlled trial.

Intra-accumbens baclofen, but not muscimol, increases second order instrumental responding for food reward in rats.

Structure of an MmyB-like regulator from C. aurantiacus, member of a new transcription factor family linked to antibiotic metabolism in actinomycetes.

A novel first aid stretcher for immobilization and transportation of spine injured patients.

No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke.

Activation of P2X7 promotes cerebral edema and neurological injury after traumatic brain injury in mice.

Transcript profile of the response of two soybean genotypes to potassium deficiency.

Looping mediated interaction between the promoter and 3' UTR regulates type II collagen expression in chondrocytes.

Transcriptional response of peripheral blood mononuclear cells from cattle infected with Mycobacterium bovis.

Adaptation in sound localization processing induced by interaural time difference in amplitude envelope at high frequencies.

Progressive increase of matrix metalloprotease-9 and interleukin-8 serum levels during carcinogenic process in human colorectal tract.

Contribution of hypothermia and CB1 receptor activation to protective effects of TAK-937, a cannabinoid receptor agonist, in rat transient MCAO model.

Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis.

Local arginase inhibition during early reperfusion mediates cardioprotection via increased nitric oxide production.

Perinatal maternal administration of Lactobacillus paracasei NCC 2461 prevents allergic inflammation in a mouse model of birch pollen allergy.

Correction: Quantification of Hepatic Iron Concentration in Chronic Viral Hepatitis: Usefulness of T2-weighted Single-Shot Spin-Echo Echo-Planar MR Imaging.

Epidemiological characteristics and underlying risk factors for mortality during the autumn 2009 pandemic wave in Mexico.

Cord blood leptin levels of healthy neonates are associated with IFN-γ production by cord blood T-cells.

Amino acid transporter genes are essential for FLO11-dependent and FLO11-independent biofilm formation and invasive growth in Saccharomyces cerevisiae.

Cold storage of rat hepatocyte suspensions for one week in a customized cold storage solution--preservation of cell attachment and metabolism.

Fluctuating helical asymmetry and morphology of snails (Gastropoda) in divergent microhabitats at 'Evolution Canyons I and II,' Israel.

The transcription factor c-Jun protects against liver damage following activated β-Catenin signaling.

Correction: Bmi-1 Absence Causes Premature Brain Degeneration

Characterization of neurophysiologic and neurocognitive biomarkers for use in genomic and clinical outcome studies of schizophrenia.

Screening strategies for tuberculosis prevalence surveys: the value of chest radiography and symptoms.

Reliability of the peer-review process for adverse event rating.

Characteristics of plasmids in multi-drug-resistant Enterobacteriaceae isolated during prospective surveillance of a newly opened hospital in Iraq.

Correction: Low-Pathogenic Avian Influenza Viruses in Wild House Mice.

Cyclosporine treatment reduces oxygen free radical generation and oxidative stress in the brain of hypoxia-reoxygenated newborn piglets.

Mg2+ in the major groove modulates B-DNA structure and dynamics.

Correction: Evolution of Eye Morphology and Rhodopsin Expression in the Drosophila melanogaster Species Subgroup

Functional anatomy of the masking level difference, an fMRI study.

Correction: Molecular Epidemiology of Serogroup B in Brazil.

Correction: Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees

It's not just lunch: extra-pair commensality can trigger sexual jealousy.

Correction: HIV Knowledge and Associated Factors among Internet-Using Men Who Have Sex with Men (MSM) in South Africa and the United States.

Comparative transcriptional analysis of clinically relevant heat stress response in Clostridium difficile strain 630.

Effects of exogenous cholecystokinin octapeptide on acquisition of naloxone precipitated withdrawal induced conditioned place aversion in rats.

Amelioration of experimental acute pancreatitis with Dachengqi Decoction via regulation of necrosis-apoptosis switch in the pancreatic acinar cell.

N-acetylcysteine protects rats with chronic renal failure from gadolinium-chelate nephrotoxicity.

Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses.

Viewing loved faces inhibits defense reactions: a health-promotion mechanism?

8,9-Epoxyeicosatrienoic acid inhibits antibody production of B lymphocytes in mice.

Mathematical modelling long-term effects of replacing Prevnar7 with Prevnar13 on invasive pneumococcal diseases in England and Wales.

Correction: Gene Transfer to Chicks Using Lentiviral Vectors Administered via the Embryonic Chorioallantoic Membrane

Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.

Evaluation of persistence of resistant variants with ultra-deep pyrosequencing in chronic hepatitis C patients treated with telaprevir.

Liver enzyme abnormalities and associated risk factors in HIV patients on efavirenz-based HAART with or without tuberculosis co-infection in Tanzania.

UNC-41/stonin functions with AP2 to recycle synaptic vesicles in Caenorhabditis elegans.

Developmental gene expression profiling along the tonotopic axis of the mouse cochlea.

Estrogen leads to reversible hair cycle retardation through inducing premature catagen and maintaining telogen.

Threshold of musculoskeletal pain intensity for increased risk of long-term sickness absence among female healthcare workers in eldercare.

Enhancing the use of Argos satellite data for home range and long distance migration studies of marine animals.

Correction: Molecular Characterisation of Transport Mechanisms at the Developing Mouse Blood–CSF Interface: A Transcriptome Approach.

Derivation of corneal endothelial cell-like cells from rat neural crest cells in vitro.

Development and validation of a high throughput system for discovery of antigens for autoantibody detection.

DIOL triterpenes block profibrotic effects of angiotensin II and protect from cardiac hypertrophy.

Identification of tyrosine-9 of MAVS as critical target for inducible phosphorylation that determines activation.

Is human cytomegalovirus infection associated with hypertension? The United States National Health and Nutrition Examination Survey 1999-2002.

Nuttalliella namaqua (Ixodoidea: Nuttalliellidae): first description of the male, immature stages and re-description of the female.

Salvage liver transplantation for patients with recurrent hepatocellular carcinoma after curative resection.

Genomic characterization of Listeria monocytogenes strains involved in a multistate listeriosis outbreak associated with cantaloupe in US.

Towards predicting basin-wide invertebrate organic biomass and production in marine sediments from a coastal sea.

Serum α-tocopherol and γ-tocopherol concentrations and prostate cancer risk in the PLCO Screening Trial: a nested case-control study.

New strategies for echocardiographic evaluation of left ventricular function in a mouse model of long-term myocardial infarction.

Validating a shortened depression scale (10 item CES-D) among HIV-positive people in British Columbia, Canada.

Loss of activating EGFR mutant gene contributes to acquired resistance to EGFR tyrosine kinase inhibitors in lung cancer cells.

Osteomimicry of mammary adenocarcinoma cells in vitro; increased expression of bone matrix proteins and proliferation within a 3D collagen environment.

On the blink: the importance of target-distractor similarity in eliciting an attentional blink with faces.

Rapid, long-distance dispersal by pumice rafting.

An automated flow for directed evolution based on detection of promiscuous scaffolds using spatial and electrostatic properties of catalytic residues.

Transitions in fertility for Brazilian women: an analysis of impact factors.

Correction: Novel, Real-Time Cell Analysis for Measuring Viral Cytopathogenesis and the Efficacy of Neutralizing Antibodies to the 2009 Influenza A (H1N1) Virus.

Tolerability of a fully maturated cheese in cow's milk allergic children: biochemical, immunochemical, and clinical aspects.

MicroRNA 107 partly inhibits endothelial progenitor cells differentiation via HIF-1β.

qPMS7: a fast algorithm for finding (ℓ, d)-motifs in DNA and protein sequences.

Evolution of growth habit, inflorescence architecture, flower size, and fruit type in Rubiaceae: its ecological and evolutionary implications.

In vivo determination of mouse olfactory mucus cation concentrations in normal and inflammatory states.

Effect of reference genome selection on the performance of computational methods for genome-wide protein-protein interaction prediction.

Drosophila motor neuron retraction during metamorphosis is mediated by inputs from TGF-β/BMP signaling and orphan nuclear receptors.

Urinary aminopeptidase activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated rats.

Cytotoxic T-lymphocyte associated antigen 4 polymorphisms and asthma risk: a meta-analysis.

Cortical actin nanodynamics determines nitric oxide release in vascular endothelium.

Correction: Dynamics of Mechanical Signal Transmission through Prestressed Stress Fibers

A Wnt/beta-catenin pathway antagonist Chibby binds Cenexin at the distal end of mother centrioles and functions in primary cilia formation.

Foxi2 is an animally localized maternal mRNA in Xenopus, and an activator of the zygotic ectoderm activator Foxi1e.

Correction: Quantification of Hepatic Iron Concentration in Chronic Viral Hepatitis: Usefulness of T2-weighted Single-Shot Spin-Echo Echo-Planar MR Imaging

Genetic variations in a PTEN/AKT/mTOR axis and prostate cancer risk in a Chinese population.

Dengue virus infection mediates HMGB1 release from monocytes involving PCAF acetylase complex and induces vascular leakage in endothelial cells.

Pituitary-specific overexpression of porcine follicle-stimulating hormone leads to improvement of female fecundity in BAC transgenic mice.

Temporal separation of aggregation and ubiquitination during early inclusion formation in transgenic mice carrying the Huntington's disease mutation.

Correction: Micro-Raman Spectroscopy of Silver Nanoparticle Induced Stress on Optically-Trapped Stem Cells

The effects of simvastatin or interferon-α on infectivity of human norovirus using a gnotobiotic pig model for the study of antivirals.

Size structure of marine soft-bottom macrobenthic communities across natural habitat gradients: implications for productivity and ecosystem function.

Correction: Expensive Egos: Narcissistic Males Have Higher Cortisol

Association of MDM2 SNP309 variation with lung cancer risk: evidence from 7196 cases and 8456 controls.

Allele copy number and underlying pathology are associated with subclinical severity in equine type 1 polysaccharide storage myopathy (PSSM1).

β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.

Correction: Changes in Health Perceptions after Exposure to Human Suffering: Using Discrete Emotions to Understand Underlying Processes.

Long-lasting LTP requires neither repeated trains for its induction nor protein synthesis for its development.

Tristetraprolin inhibits poly(A)-tail synthesis in nuclear mRNA that contains AU-rich elements by interacting with poly(A)-binding protein nuclear 1.

Restoration of dioxin-induced damage to fetal steroidogenesis and gonadotropin formation by maternal co-treatment with α-lipoic acid.

Correction: Search Filters for Finding Prognostic and Diagnostic Prediction Studies in Medline to Enhance Systematic Reviews.

Antiretroviral treatment for HIV in rural Uganda: two-year treatment outcomes of a prospective health centre/community-based and hospital-based cohort.

Process-driven inference of biological network structure: feasibility, minimality, and multiplicity.

Validation of exposure visualization and audible distance emission for navigated temporal bone drilling in phantoms.

Angiotensin II-induced mitochondrial Nox4 is a major endogenous source of oxidative stress in kidney tubular cells.

Detection of quorum sensing signal molecules and identification of an autoinducer synthase gene among biofilm forming clinical isolates of Acinetobacter spp.

The dose and dose-rate effects of paternal irradiation on transgenerational instability in mice: a radiotherapy connection.

Bitter taste stimuli induce differential neural codes in mouse brain.

Assessing the risk that Phytophthora melonis can develop a point mutation (V1109L) in CesA3 conferring resistance to carboxylic acid amide fungicides.

Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma.

CD4+CD25+ regulatory T cell depletion modulates anxiety and depression-like behaviors in mice.

Energetics of Ortho-7 (oxime drug) translocation through the active-site gorge of tabun conjugated acetylcholinesterase.

A study of a decade of road traffic accidents in Benghazi-Libya: 2001 to 2010.

Polyglutamine aggregate structure in vitro and in vivo; new avenues for coherent anti-Stokes Raman scattering microscopy.

A new antifibrotic target of Ac-SDKP: inhibition of myofibroblast differentiation in rat lung with silicosis.

Serratia odorifera a midgut inhabitant of Aedes aegypti mosquito enhances its susceptibility to dengue-2 virus.

Structural insights into the effector-immunity system Tse1/Tsi1 from Pseudomonas aeruginosa.

HIV model parameter estimates from interruption trial data including drug efficacy and reservoir dynamics.

Receptor activator of NF-kappaB and podocytes: towards a function of a novel receptor-ligand pair in the survival response of podocyte injury.

Changes in semi-arid plant species associations along a livestock grazing gradient.

Alzheimer's-related peptide amyloid-β plays a conserved role in angiogenesis.

14-3-3θ is a binding partner of rat Eag1 potassium channels.

Heart failure and preserved left ventricular function: long term clinical outcome.

Pathogenicity of autoantibodies in anti-p200 pemphigoid.

Testing the effectiveness of an international conservation agreement: marketplace forensics and CITES caviar trade regulation.

Synergy between vancomycin and nafcillin against Staphylococcus aureus in an in vitro pharmacokinetic/pharmacodynamic model.

Identifying protein phosphorylation sites with kinase substrate specificity on human viruses.

p14ARF post-transcriptional regulation of nuclear cyclin D1 in MCF-7 breast cancer cells: discrimination between a good and bad prognosis?

Increase in caesarean deliveries after the Australian Private Health Insurance Incentive policy reforms.

Remote ischemic conditioning to protect against ischemia-reperfusion injury: a systematic review and meta-analysis.

A preliminary study of copy number variation in Tibetans.

Inhibition of E2F1/CDK1 pathway attenuates neuronal apoptosis in vitro and confers neuroprotection after spinal cord injury in vivo.

Learning that circumcision is protective against HIV: risk compensation among men and women in Cape Town, South Africa.

A quorum sensing-disrupting brominated thiophenone with a promising therapeutic potential to treat luminescent vibriosis.

High phobic anxiety is related to lower leukocyte telomere length in women.

CD154 blockade alters innate immune cell recruitment and programs alloreactive CD8+ T cells into KLRG-1(high) short-lived effector T cells.

A novel way to grow hemozoin-like crystals in vitro and its use to screen for hemozoin inhibiting antimalarial compounds.

PGC-1α is dispensable for exercise-induced mitochondrial biogenesis in skeletal muscle.

A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6.

Tweeting the meeting: an in-depth analysis of Twitter activity at Kidney Week 2011.

Oleanolic acid reduces hyperglycemia beyond treatment period with Akt/FoxO1-induced suppression of hepatic gluconeogenesis in type-2 diabetic mice.

Promoter strength driving TetR determines the regulatory properties of Tet-controlled expression systems.

A characterization of internet dating network structures among nordic men who have sex with men.

Establishment of animal model of dual liver transplantation in rat.

Growth, thermal and spectral properties of Er3+-doped and Er3+/Yb3+-codoped Li3Ba2La3(WO4)8 crystals.

Protein tyrosine phosphatase PTP1B is involved in hippocampal synapse formation and learning.

Estrogens induce expression of membrane-associated estrogen receptor α isoforms in lactotropes.

Fluid flow along venous adventitia in rabbits: is it a potential drainage system complementary to vascular circulations?

The integrin-ligand interaction regulates adhesion and migration through a molecular clutch.

MIP-1δ activates NFATc1 and enhances osteoclastogenesis: involvement of both PLCγ2 and NFκB signaling.

Wallerian degeneration in central nervous system: dynamic associations between diffusion indices and their underlying pathology.

The dengue vector Aedes aegypti contains a functional high mobility group box 1 (HMGB1) protein with a unique regulatory C-terminus.

Methods of patient warming during abdominal surgery.

Invasibility of a nutrient-poor pasture through resident and non-resident herbs is controlled by litter, gap size and propagule pressure.

Polymorphisms in the ERCC5 gene and risk of esophageal squamous cell carcinoma (ESCC) in Eastern Chinese populations.

Work-related exhaustion and telomere length: a population-based study.

25-Hydroxyvitamin D depletion does not exacerbate MPTP-induced dopamine neuron damage in mice.

Correction: Synaptotagmin-2 Is a Reliable Marker for Parvalbumin Positive Inhibitory Boutons in the Mouse Visual Cortex

Identification and dissection of four major QTL affecting milk fat content in the German Holstein-Friesian population.

Effect of short-term thyroxine administration on energy metabolism and mitochondrial efficiency in humans.

Correction: A Powerful Test of Parent-of-Origin Effects for Quantitative Traits Using Haplotypes

Beta-mecaptoethanol suppresses inflammation and induces adipogenic differentiation in 3T3-F442A murine preadipocytes.

High risk of ART non-adherence and delay of ART initiation among HIV positive double orphans in Kigali, Rwanda.

Stimulation of Wnt/ß-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotype.

Antigen binding characteristics of immunoglobulin free light chains: crosslinking by antigen is essential to induce allergic inflammation.

The bitter truth about morality: virtue, not vice, makes a bland beverage taste nice.

Convergence and divergence in the evolution of cat skulls: temporal and spatial patterns of morphological diversity.

Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi.

Dealing with varying detection probability, unequal sample sizes and clumped distributions in count data.

Identification of factors contributing to variability in a blood-based gene expression test.

Downregulation of the NHE3-binding PDZ-adaptor protein PDZK1 expression during cytokine-induced inflammation in interleukin-10-deficient mice.

Correlation of HER2, p95HER2 and HER3 expression and treatment outcome of lapatinib plus capecitabine in her2-positive metastatic breast cancer.

Developmental changes of BOLD signal correlations with global human EEG power and synchronization during working memory.

The immunomodulatory activity of meningococcal lipoprotein Ag473 depends on the conformation made up of the lipid and protein moieties.

Activity-dependent subcellular cotrafficking of the small GTPase Rem2 and Ca2+/CaM-dependent protein kinase IIα.

Splice variants of Na(V)1.7 sodium channels have distinct β subunit-dependent biophysical properties.

Significant rewiring of the transcriptome and proteome of an Escherichia coli strain harboring a tailored exogenous global regulator IrrE.

Prevalence of and risk factors for trachoma in Kano state, Nigeria.

Comparison of apolipoprotein (apoB/apoA-I) and lipoprotein (total cholesterol/HDL) ratio determinants. Focus on obesity, diet and alcohol intake.

Microsatellites in the estrogen receptor (ESR1, ESR2) and androgen receptor (AR) genes and breast cancer risk in African American and Nigerian women.

Early evolution and historical biogeography of fishflies (Megaloptera: Chauliodinae): implications from a phylogeny combining fossil and extant taxa.

Association between genetic variants in DNA and histone methylation and telomere length.

Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responses.

Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif.

Detection of Staphylococcus aureus delta-toxin production by whole-cell MALDI-TOF mass spectrometry.

Amniotic-fluid-derived mesenchymal stem cells overexpressing interleukin-1 receptor antagonist improve fulminant hepatic failure.

Plasma cathepsin S and cystatin C levels and risk of abdominal aortic aneurysm: a randomized population-based study.

Cerebral activations related to ballistic, stepwise interrupted and gradually modulated movements in Parkinson patients.

Absence of PTHrP nuclear localization and carboxyl terminus sequences leads to abnormal brain development and function.

Gαo and Gαq regulate the expression of daf-7, a TGFβ-like gene, in Caenorhabditis elegans.

Contribution of the -160C/A polymorphism in the E-cadherin promoter to cancer risk: a meta-analysis of 47 case-control studies.

Common genetic variants associated with sudden cardiac death: the FinSCDgen study.

Rapid detection and identification of human hookworm infections through high resolution melting (HRM) analysis.

Influence of connectivity, wild prey and disturbance on occupancy of tigers in the human-dominated western Terai Arc Landscape.

Retention in a NGO supported antiretroviral program in the Democratic Republic of Congo.

Salvinorin A administration after global cerebral hypoxia/ischemia preserves cerebrovascular autoregulation via kappa opioid receptor in piglets.

Network centrality of metro systems.

Investigating the production of foreign membrane proteins in tobacco chloroplasts: expression of an algal plastid terminal oxidase.

Correction: Recruiting a New Substrate for Triacylglycerol Synthesis in Plants: The Monoacylglycerol Acyltransferase Pathway

Fluorine-19 magnetic resonance angiography of the mouse.

Insulin-increased L-arginine transport requires A(2A) adenosine receptors activation in human umbilical vein endothelium.

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition.

Different genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general population.

Mapping paratope on antithrombotic antibody 6B4 to epitope on platelet glycoprotein Ibalpha via molecular dynamic simulations.

Loss of DJ-1 does not affect mitochondrial respiration but increases ROS production and mitochondrial permeability transition pore opening.

Autism spectrum disorders in the Stockholm Youth Cohort: design, prevalence and validity.

The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages.

Mycobacterium tuberculosis infection interferes with HIV vaccination in mice.

Enhancing adverse drug event detection in electronic health records using molecular structure similarity: application to pancreatitis.

Correction: NKT Cells Stimulated by Long Fatty Acyl Chain Sulfatides Significantly Reduces the Incidence of Type 1 Diabetes in Nonobese Diabetic Mice

Identification of catalytic residues using a novel feature that integrates the microenvironment and geometrical location properties of residues.

Interspecies avian brain chimeras reveal that large brain size differences are influenced by cell-interdependent processes.

Platelets induce apoptosis during sepsis in a contact-dependent manner that is inhibited by GPIIb/IIIa blockade.

Maternal smoking during pregnancy predicts adult offspring cardiovascular risk factors - evidence from a community-based large birth cohort study.

Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility.

Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele.

Sorting the wheat from the chaff: identifying miRNAs in genomic survey sequences of Triticum aestivum chromosome 1AL.

TNF-overexpression in Borna disease virus-infected mouse brains triggers inflammatory reaction and epileptic seizures.

Correction: Habitat and Scale Shape the Demographic Fate of the Keystone Sea Urchin Paracentrotus lividus in Mediterranean Macrophyte Communities

Establishment and characterization of a buffalo (Bubalus bubalis) mammary epithelial cell line.

Correction: Synaptotagmin-2 Is a Reliable Marker for Parvalbumin Positive Inhibitory Boutons in the Mouse Visual Cortex.

Cytoplasmic sulfurtransferases in the purple sulfur bacterium Allochromatium vinosum: evidence for sulfur transfer from DsrEFH to DsrC.

Gene expression from bronchoscopy obtained tumour samples as a predictor of outcome in advanced inoperable lung cancer.

Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel.

Human macrophages and dendritic cells can equally present MART-1 antigen to CD8(+) T cells after phagocytosis of gamma-irradiated melanoma cells.

Correction: Extensions of MADM (Mosaic Analysis with Double Markers) in Mice.

The SNP (rs2230500) in PRKCH decreases the risk of carotid intima-media thickness in a Chinese young adult population.

Sub-optimal vitamin B-12 levels among ART-naïve HIV-positive individuals in an urban cohort in Uganda.

Vaccination behaviour influences self-report of influenza vaccination status: a cross-sectional study among health care workers.

Zidovudine exposure in HIV-1 infected Tanzanian women increases mitochondrial DNA levels in placenta and umbilical cords.

Modulation of intestinal inflammation by yeasts and cell wall extracts: strain dependence and unexpected anti-inflammatory role of glucan fractions.

Correlation between base-excision repair gene polymorphisms and levels of in-vitro BPDE-induced DNA adducts in cultured peripheral blood lymphocytes.

Infant rule learning: advantage language, or advantage speech?

Genome wide assessment of young onset Parkinson's disease from Finland.

Physalin F induces cell apoptosis in human renal carcinoma cells by targeting NF-kappaB and generating reactive oxygen species.

Acid sensing ion channel 1 in lateral hypothalamus contributes to breathing control.

(Pro)renin receptor triggers distinct angiotensin II-independent extracellular matrix remodeling and deterioration of cardiac function.

Correction: Search Filters for Finding Prognostic and Diagnostic Prediction Studies in Medline to Enhance Systematic Reviews

GLI2 regulates TGF-β1 in human CD4+ T cells: implications in cancer and HIV pathogenesis.

Probing cocaine-antibody interactions in buffer and human serum.

Viral reverse transcriptases show selective high affinity binding to DNA-DNA primer-templates that resemble the polypurine tract.

Uptake of voluntary counselling and testing among young people participating in an HIV prevention trial: comparison of opt-out and opt-in strategies.

No difference in keratin thickness between inner and outer foreskins from elective male circumcisions in Rakai, Uganda.

Harborview burns--1974 to 2009.

Planktonic aggregates of Staphylococcus aureus protect against common antibiotics.

Effect of adjuvants on responses to skin immunization by microneedles coated with influenza subunit vaccine.

Correction: Dynamics of Mechanical Signal Transmission through Prestressed Stress Fibers.

Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism.

IMG/M-HMP: a metagenome comparative analysis system for the Human Microbiome Project.

Impact of health literacy in patients with chronic musculoskeletal disease--systematic review.

Mortality, neonatal morbidity and two year follow-up of extremely preterm infants born in The Netherlands in 2007.

Diabetes care provision in UK primary care practices.

Hydrogen peroxide alters splicing of soluble guanylyl cyclase and selectively modulates expression of splicing regulators in human cancer cells.

The role of activity in synaptic degeneration in a protein misfolding disease, prion disease.

Memantine inhibits α3β2-nAChRs-mediated nitrergic neurogenic vasodilation in porcine basilar arteries.

Tumor associated macrophage × cancer cell hybrids may acquire cancer stem cell properties in breast cancer.

The association between cold spells and pediatric outpatient visits for asthma in Shanghai, China.

Novel bacteriophages containing a genome of another bacteriophage within their genomes.

The Ca2+/calcineurin-dependent signaling pathway in the gray mold Botrytis cinerea: the role of calcipressin in modulating calcineurin activity.

Parkin promotes degradation of the mitochondrial pro-apoptotic ARTS protein.

Second-chance signal transduction explains cooperative flagellar switching.

Regional differences in AIDS and non-AIDS related mortality in HIV-positive individuals across Europe and Argentina: the EuroSIDA study.

2-Color calcium pump reveals closure of the cytoplasmic headpiece with calcium binding.

p53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiation.

Prevalence of chronic kidney disease and progression of disease over time among patients enrolled in the Houston West Nile virus cohort.

Investigating the global dispersal of chickens in prehistory using ancient mitochondrial DNA signatures.

Correction: A Synthetic Chloride Channel Restores Chloride Conductance in Human Cystic Fibrosis Epithelial Cells.

Migration routes and strategies in a highly aerial migrant, the common swift Apus apus, revealed by light-level geolocators.

Age and sex composition of seals killed by polar bears in the eastern Beaufort Sea.

Prediction of expected years of life using whole-genome markers.

Resource use and costs associated with coeliac disease before and after diagnosis in 3,646 cases: results of a UK primary care database analysis.

Sensitization of human pancreatic cancer cells harboring mutated K-ras to apoptosis.

Cysteinyl leukotriene signaling aggravates myocardial hypoxia in experimental atherosclerotic heart disease.

Electron paramagnetic resonance highlights that the oxygen effect contributes to the radiosensitizing effect of paclitaxel.

The sedative effect of non-alcoholic beer in healthy female nurses.

A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C.

Comparing trawl and creel fishing for Norway lobster (Nephrops norvegicus): biological and economic considerations.

Promoters are differentially sensitive to N-terminal mutant huntingtin-mediated transcriptional repression.

Transcriptome analysis of early surface-associated growth of Shewanella oneidensis MR-1.

Matrix metalloproteinase-2 promotes αvβ3 integrin-mediated adhesion and migration of human melanoma cells by cleaving fibronectin.

Furin overexpression suppresses tumor growth and predicts a better postoperative disease-free survival in hepatocellular carcinoma.

Prevalence and associations of steep cornea/keratoconus in Greater Beijing. The Beijing Eye Study.

Correction: On the Evolution of Hexose Transporters in Kinetoplastid Potozoans.

Zoledronate inhibits ischemia-induced neovascularization by impairing the mobilization and function of endothelial progenitor cells.

Granzyme B is dispensable in the development of diabetes in non-obese diabetic mice.

Identifying regional variation in the prevalence of postpartum haemorrhage: a systematic review and meta-analysis.

Ribavirin exerts differential effects on functions of Cd4+ Th1, Th2, and regulatory T cell clones in hepatitis C.

Longitudinal MRI study on the natural history of carotid artery plaques in symptomatic patients.

Schmallenberg virus infection of adult type I interferon receptor knock-out mice.

Incidence of epileptiform EEG activity in children during mask induction of anaesthesia with brief administration of 8% sevoflurane.

Single-cell pulsed-field gel electrophoresis to detect the early stage of DNA fragmentation in human sperm nuclei.

Factors affecting birth weight of a newborn--a community based study in rural Karnataka, India.

Correction: Xer Recombinase and Genome Integrity in , a Pathogen without Topoisomerase IV.

Nanoparticle-mediated local delivery of an antisense TGF-β1 construct inhibits intimal hyperplasia in autogenous vein grafts in rats.

Correction: Respective Prognostic Value of Genomic Grade and Histological Proliferation Markers in Early Stage (pN0) Breast Carcinoma.

Quantification of HER expression and dimerization in patients' tumor samples using time-resolved Förster resonance energy transfer.

In vitro expanded stem cells from the developing retina fail to generate photoreceptors but differentiate into myelinating oligodendrocytes.

Assessment of TP53 mutations in benign and malignant salivary gland neoplasms.

Concerted perturbation observed in a hub network in Alzheimer's disease.

The CUPID (Cultural and Psychosocial Influences on Disability) study: methods of data collection and characteristics of study sample.

DNase SISPA-next generation sequencing confirms Schmallenberg virus in Belgian field samples and identifies genetic variation in Europe.

Identification and characterization of the cognate anti-sigma factor and specific promoter elements of a T. tengcongensis ECF sigma factor.

Efficient production of pyruvate from DL-lactate by the lactate-utilizing strain Pseudomonas stutzeri SDM.

Gene silencing of Toll-like receptor 2 inhibits proliferation of human liver cancer cells and secretion of inflammatory cytokines.

Pharyngeal microflora disruption by antibiotics promotes airway hyperresponsiveness after respiratory syncytial virus infection.

Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS.

HIV and dyadic intervention: an interdependence and communal coping analysis.

Human papillomavirus-16 infection in advanced oral cavity cancer patients is related to an increased risk of distant metastases and poor survival.

Metabolomics approach for analyzing the effects of exercise in subjects with type 1 diabetes mellitus.

Effect of intravitreal anti-vascular endothelial growth factor therapy on the risk of arterial thromboembolic events: a meta-analysis.

Intracellular overexpression of HIV-1 Nef impairs differentiation and maturation of monocytic precursors towards dendritic cells.

Anti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo.

Increases in individualistic words and phrases in American books, 1960-2008.

Bayesian Latent Class Models in malaria diagnosis.

Immune response and anti-microbial peptides expression in Malpighian tubules of Drosophila melanogaster is under developmental regulation.

Tim-3 negatively regulates cytotoxicity in exhausted CD8+ T cells in HIV infection.

Impact of five nights of sleep restriction on glucose metabolism, leptin and testosterone in young adult men.

Enhanced antitumor efficacy of a vascular disrupting agent combined with an antiangiogenic in a rat liver tumor model evaluated by multiparametric MRI.

Monitoring of human cytomegalovirus and virus-specific T-cell response in young patients receiving allogeneic hematopoietic stem cell transplantation.

The timing of learning before night-time sleep differentially affects declarative and procedural long-term memory consolidation in adolescents.

Relationship between periodontitis-related antibody and frequent exacerbations in chronic obstructive pulmonary disease.

Mitochondrial genome variations in advanced stage endometriosis: a study in South Indian population.

Effect of multiple parasitic infections on the tolerance to pollutant contamination.

Correction: Fact or Factitious? A Psychobiological Study of Authentic and Simulated Dissociative Identity States

Functional subdivision of group-ICA results of fMRI data collected during cinema viewing.

Independent studies using deep sequencing resolve the same set of core bacterial species dominating gut communities of honey bees.

Pancreatic cancer cells enhance the ability of collagen internalization during epithelial-mesenchymal transition.

HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors.

Identification of rat ventral tegmental area GABAergic neurons.

Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer.

Genes associated with retinitis pigmentosa and allied diseases are frequently mutated in the general population.

Mycobacterium tuberculosis infection of dendritic cells leads to partially caspase-1/11-independent IL-1β and IL-18 secretion but not to pyroptosis.

Similarities of Drosophila rab GTPases based on expression profiling: completion and analysis of the rab-Gal4 kit.

Genetic signals of demographic expansion in Downy Woodpecker (Picoides pubescens) after the last North American glacial maximum.

Dietary fibre improves first-phase insulin secretion in overweight individuals.

Occurrence of natural vertical transmission of dengue-2 and dengue-3 viruses in Aedes aegypti and Aedes albopictus in Fortaleza, Ceará, Brazil.

Platelet-derived Toll-like receptor 4 (Tlr-4) is sufficient to promote microvascular thrombosis in endotoxemia.

Matrix-M™ adjuvant induces local recruitment, activation and maturation of central immune cells in absence of antigen.

Mapping wintering waterfowl distributions using weather surveillance radar.

Increased CD39 nucleotidase activity on microparticles from patients with idiopathic pulmonary arterial hypertension.

Constructing endophenotypes of complex diseases using non-negative matrix factorization and adjusted rand index.

Correction: Xer Recombinase and Genome Integrity in Helicobacter pylori, a Pathogen without Topoisomerase IV

Measuring animal welfare within a reintroduction: an assessment of different indices of stress in water voles Arvicola amphibius.

Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment.

Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection.

Plant lectin can target receptors containing sialic acid, exemplified by podoplanin, to inhibit transformed cell growth and migration.

Hepatitis B viral DNA decline at loss of HBeAg is mainly explained by reduced cccDNA load--down-regulated transcription of PgRNA has limited impact.

Fra-1/AP-1 transcription factor negatively regulates pulmonary fibrosis in vivo.

Survival, growth and reproduction of non-native Nile tilapia II: fundamental niche projections and invasion potential in the northern Gulf of Mexico.

Trimetazidine protects against smoking-induced left ventricular remodeling via attenuating oxidative stress, apoptosis, and inflammation.

Correction: The Structure of Mutations and the Evolution of Cooperation

Assessing whether alpha-tubulin sequences are suitable for phylogenetic reconstruction of Ciliophora with insights into its evolution in euplotids.

A 46,XY female DSD patient with bilateral gonadoblastoma, a novel SRY missense mutation combined with a WT1 KTS splice-site mutation.

Effect of benfotiamine on advanced glycation endproducts and markers of endothelial dysfunction and inflammation in diabetic nephropathy.

Genetic connectivity between north and south Mid-Atlantic Ridge chemosynthetic bivalves and their symbionts.

Numerous clones resistant to Phytophthora palmivora in the "Guiana" genetic group of Theobroma cacao L.

Simulating molecular mechanisms of the MDM2-mediated regulatory interactions: a conformational selection model of the MDM2 lid dynamics.

Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling.

Assessing the quality of reports about randomized controlled trials of acupuncture treatment on Diabetic Peripheral Neuropathy.

Effect of plasma membrane cholesterol depletion on glucose transport regulation in leukemia cells.

The heterogeneous HLA genetic makeup of the Swiss population.

Correction: Changes in Health Perceptions after Exposure to Human Suffering: Using Discrete Emotions to Understand Underlying Processes

Altered biomarkers of mucosal immunity and reduced vaginal Lactobacillus concentrations in sexually active female adolescents.

Periostin facilitates skin sclerosis via PI3K/Akt dependent mechanism in a mouse model of scleroderma.

Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats.

Rubella epidemics and genotypic distribution of the rubella virus in Shandong Province, China, in 1999-2010.

Transscleral diode photocoagulation of large retinal and choroidal vascular lesions.

Lipocalin prostaglandin D synthase and PPARγ2 coordinate to regulate carbohydrate and lipid metabolism in vivo.

To beg, or not to beg? That is the question: mangabeys modify their production of requesting gestures in response to human's attentional states.

The T box transcription factor TBX2 promotes epithelial-mesenchymal transition and invasion of normal and malignant breast epithelial cells.

The uncoordinated-5 homolog B receptor affects hepatic ischemia reperfusion injury.

Comparison of methods for competitive tests of pathway analysis.

Short-term forest management effects on a long-lived ectotherm.

Correction: Temporal Dissection of K-ras Mutant and Using a Regulatable K-ras Mouse Allele.

Microbial diversity of genital ulcer disease in men enrolled in a randomized trial of male circumcision in Kisumu, Kenya.

NPY and VGF immunoreactivity increased in the arcuate nucleus, but decreased in the nucleus of the Tractus Solitarius, of type-II diabetic patients.

Correction: Mind Bomb-1 in Dendritic Cells Is Specifically Required for Notch-mediated T Helper Type 2 Differentiation.

Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone.

Dopamine receptor-interacting protein 78 acts as a molecular chaperone for CCR5 chemokine receptor signaling complex organization.

β,β-Dimethylacrylshikonin induces mitochondria dependent apoptosis through ERK pathway in human gastric cancer SGC-7901 cells.

Vitamin D is a major determinant of bone mineral density at school age.

Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38α kinase.

Minocycline modulates human social decision-making: possible impact of microglia on personality-oriented social behaviors.

Efficacy of E. officinalis on the cariogenic properties of Streptococcus mutans: a novel and alternative approach to suppress quorum-sensing mechanism.

Novel RNAi-mediated approach to G protein-coupled receptor deorphanization: proof of principle and characterization of a planarian 5-HT receptor.

β1 adrenergic receptor polymorphisms and heart failure: a meta-analysis on susceptibility, response to β-blocker therapy and prognosis.

Plasma protein characteristics of long-term hemodialysis survivors.

Analysis of autophagy genes in microalgae: Chlorella as a potential model to study mechanism of autophagy.

Cumulative cultural evolution and demography.

Multiple activities of LigB potentiate virulence of Leptospira interrogans: inhibition of alternative and classical pathways of complement.

Transcriptome of the plant virus vector Graminella nigrifrons, and the molecular interactions of maize fine streak rhabdovirus transmission.

Induction of heme oxygenase-1 inhibits cell death in crotonaldehyde-stimulated HepG2 cells via the PKC-δ-p38-Nrf2 pathway.

Hydrogen sulfide inhibits the development of atherosclerosis with suppressing CX3CR1 and CX3CL1 expression.

The organelle genomes of Hassawi rice (Oryza sativa L.) and its hybrid in saudi arabia: genome variation, rearrangement, and origins.

Using poison center exposure calls to predict methadone poisoning deaths.

Dietary factors impact on the association between CTSS variants and obesity related traits.

Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma.

Binding of hnRNP H and U2AF65 to respective G-codes and a poly-uridine tract collaborate in the N50-5'ss selection of the REST N exon in H69 cells.

ACPA-negative RA consists of two genetically distinct subsets based on RF positivity in Japanese.

The fate of the missing spores--patterns of realized dispersal beyond the closest vicinity of a sporulating moss.

The molecular effects of a polymorphism in the 5'UTR of solute carrier family 44, member 5 that is associated with birth weight in Holsteins.

Proteomic analysis of PKCγ-related proteins in the spinal cord of morphine-tolerant rats.

Promoter-specific expression and imprint status of marsupial IGF2.

Correction: National Prevalence and Trends of HIV Transmitted Drug Resistance in Mexico.

The aromatase gene (CYP19A1) variants and circulating hepatocyte growth factor in postmenopausal women.

BAT3 regulates Mycobacterium tuberculosis protein ESAT-6-mediated apoptosis of macrophages.

Magnolol reduces glutamate-induced neuronal excitotoxicity and protects against permanent focal cerebral ischemia up to 4 hours.

Genetic relatedness of low solitary nests of Apis dorsata from Marang, Terengganu, Malaysia.

Smoking during pregnancy is associated with a decreased incidence of obstetric anal sphincter injuries in nulliparous women.

Correction: Ancient DNA from Hunter-Gatherer and Farmer Groups from Northern Spain Supports a Random Dispersion Model for the Neolithic Expansion into Europe.

Dynamic expression profiles from static cytometry data: component fitting and conversion to relative, "same scale" values.

Mirtazapine inhibits tumor growth via immune response and serotonergic system.

Correction: Effect of Chemical Mutagens and Carcinogens on Gene Expression Profiles in Human TK6 Cells.

Associations between apolipoprotein E genotype, diet, body mass index, and serum lipids in Lithuanian adult population.

Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglyceryl transferase gene lgt on ABC transporter function and on growth in vivo.

GmcA is a putative glucose-methanol-choline oxidoreductase required for the induction of asexual development in Aspergillus nidulans.

Retro-nasal aroma release is correlated with variations in the in-mouth air cavity volume after empty deglutition.

Liver stiffness using transient elastography is applicable to canines for hepatic disease models.

The halo effect: suppression of pink bollworm on non-Bt cotton by Bt cotton in China.

Agricultural trade networks and patterns of economic development.

The effectiveness of online cognitive behavioral treatment in routine clinical practice.

The diagnostic accuracy of urine-based Xpert MTB/RIF in HIV-infected hospitalized patients who are smear-negative or sputum scarce.

Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22.

Genome-wide transcriptional response of the archaeon Thermococcus gammatolerans to cadmium.

Regulation of interferon-β by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBM.

Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts.

Molecular hydrogen reduces LPS-induced neuroinflammation and promotes recovery from sickness behaviour in mice.

Avian BMR in marine and non-marine habitats: a test using shorebirds.

Amusia results in abnormal brain activity following inappropriate intonation during speech comprehension.

Environmental effects on compulsive tail chasing in dogs.

Vault nanocapsules as adjuvants favor cell-mediated over antibody-mediated immune responses following immunization of mice.

Correction: Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees.

EEG dynamics reflect the distinct cognitive process of optic problem solving.

Multiplex detection of B-type natriuretic peptide, cardiac troponin I and C-reactive protein with photonic suspension array.

Cell wall ingrowths in nematode induced syncytia require UGD2 and UGD3.

Exercise training improves exercise capacity and quality of life in patients with inoperable or residual chronic thromboembolic pulmonary hypertension.

Correction: Low-Pathogenic Avian Influenza Viruses in Wild House Mice

Design and update of a classification system: the UCSD map of science.

Content Factor: a measure of a journal's contribution to knowledge.

HIV-1 infection and first line ART induced differential responses in mitochondria from blood lymphocytes and monocytes: the ANRS EP45 "Aging" study.

Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue fever.

An effort to use human-based exome capture methods to analyze chimpanzee and macaque exomes.

An integrin from shrimp Litopenaeus vannamei mediated microbial agglutination and cell proliferation.

High-throughput identification and screening of novel Methylobacterium species using whole-cell MALDI-TOF/MS analysis.

Cerebrospinal fluid neopterin as marker of the meningo-encephalitic stage of Trypanosoma brucei gambiense sleeping sickness.

Sequencing of IncX-plasmids suggests ubiquity of mobile forms of a biofilm-promoting gene cassette recruited from Klebsiella pneumoniae.

Influence of Mabs on PrP(Sc) formation using in vitro and cell-free systems.

Cryptic species in putative ancient asexual darwinulids (Crustacea, Ostracoda).

Cognitive dysfunction in early multiple sclerosis: altered centrality derived from resting-state functional connectivity using magneto-encephalography.

Irinotecan (CPT-11) chemotherapy alters intestinal microbiota in tumour bearing rats.

Correction: On the Evolution of Hexose Transporters in Kinetoplastid Potozoans

When to hold that thought: an experimental study showing reduced inhibition of pre-trained associations in schizophrenia.

The stimulating effect of bright light on physical performance depends on internal time.

Downregulation of polo-like kinase 4 in hepatocellular carcinoma associates with poor prognosis.

Genetic variants in CASP3, BMP5, and IRS2 genes may influence survival in prostate cancer patients receiving androgen-deprivation therapy.

MicroRNA regulation of the synaptic plasticity-related gene Arc.

Combination treatment of rosuvastatin or atorvastatin, with regular exercise improves arterial wall stiffness in patients with coronary artery disease.

Affibody-DyLight conjugates for in vivo assessment of HER2 expression by near-infrared optical imaging.

Taking a comparative approach: analysing personality as a multivariate behavioural response across species.

Mycobacterium tuberculosis population in northwestern Russia: an update from Russian-EU/Latvian border region.

Vascular disrupting agent drug classes differ in effects on the cytoskeleton.

Proteomic identification of ADAM12 as a regulator for TGF-β1-induced differentiation of human mesenchymal stem cells to smooth muscle cells.

Structure and binding interface of the cytosolic tails of αXβ2 integrin.

Diverging trends in recent population-based survival rates in oesophageal and gastric cancer.

Interplay of Nkx3.2, Sox9 and Pax3 regulates chondrogenic differentiation of muscle progenitor cells.

Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer.

Correction: In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS

A multicriteria decision making approach for estimating the number of clusters in a data set.

Comparison between EQ-5D and SF-6D utility in rural residents of Jiangsu Province, China.

Mesenchymal stromal cells but not cardiac fibroblasts exert beneficial systemic immunomodulatory effects in experimental myocarditis.

Correction: Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance

Streptococcus pyogenes SpyCEP influences host-pathogen interactions during infection in a murine air pouch model.

Temporal patterns of medications dispensed to children and adolescents in a national insured population.

Correction: Gene Transfer to Chicks Using Lentiviral Vectors Administered via the Embryonic Chorioallantoic Membrane.

Sickness absence following coronary revascularisation. A national study of women and men of working age in Sweden 1994-2006.

Studies on the roles of clathrin-mediated membrane trafficking and zinc transporter Cis4 in the transport of GPI-anchored proteins in fission yeast.

Comparison of the predicted population coverage of tuberculosis vaccine candidates Ag85B-ESAT-6, Ag85B-TB10.4, and Mtb72f via a bioinformatics approach.

Correction: Evolutionary Responses to a Constructed Niche: Ancient Mesoamericans as a Model of Gene-Culture Coevolution.

Measurement properties of questionnaires measuring continuity of care: a systematic review.

17β-Hydroxysteroid dehydrogenase type 14 is a predictive marker for tamoxifen response in oestrogen receptor positive breast cancer.

Myeloid suppressor cell depletion augments antitumor activity in lung cancer.

High prevalence of anti-HCV antibodies in two metropolitan emergency departments in Germany: a prospective screening analysis of 28,809 patients.

CTX (crosslaps) rather than osteopontin is associated with disturbed glucose metabolism in gestational diabetes.

Correction: RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI3 Kinase/Akt Signaling Pathways

An expanded multilocus sequence typing scheme for propionibacterium acnes: investigation of 'pathogenic', 'commensal' and antibiotic resistant strains.

Synthetic spike-in standards improve run-specific systematic error analysis for DNA and RNA sequencing.

Correction: A Synthetic Chloride Channel Restores Chloride Conductance in Human Cystic Fibrosis Epithelial Cells

Correction: Gender, Obesity and Repeated Elevation of C-Reactive Protein: Data from the CARDIA Cohort

Mouse allergen, lung function, and atopy in Puerto Rican children.

Bone and energy metabolism parameters in professional cyclists during the Giro d'Italia 3-weeks stage race.

Comparison of WTC dust size on macrophage inflammatory cytokine release in vivo and in vitro.

Requirement for a uroplakin 3a-like protein in the development of zebrafish pronephric tubule epithelial cell function, morphogenesis, and polarity.

Heterosexual men and women both show a hypothalamic response to the chemo-signal androstadienone.

Dynamics of PLCγ and Src family kinase 1 interactions during nuclear envelope formation revealed by FRET-FLIM.

Increased angiogenesis and improved left ventricular function after transplantation of myoblasts lacking the MyoD gene into infarcted myocardium.

Correction: MicroRNA-141 Represses HBV Replication by Targeting PPARA.

Angiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cells.

Defence signalling triggered by Flg22 and Harpin is integrated into a different stilbene output in Vitis cells.

Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data.

Analysing humanly generated random number sequences: a pattern-based approach.

Treatment with antibiotics that interfere with peptidoglycan biosynthesis inhibits chloroplast division in the desmid Closterium.

Molecular evolution of GII-4 Norovirus strains.

Correction: In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS.

A novel viral SOCS from infectious spleen and kidney necrosis virus: interacts with Jak1 and inhibits IFN-α induced Stat1/3 activation.

The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling.

Depletion of c-Rel from cytokine gene promoters is required for chromatin reassembly and termination of gene responses to T cell activation.

Correction: HIV Knowledge and Associated Factors among Internet-Using Men Who Have Sex with Men (MSM) in South Africa and the United States

Excessive attractor instability accounts for semantic priming in schizophrenia.

Potential influences of climate and nest structure on spotted owl reproductive success: a biophysical approach.

Quality of life outcomes of antiretroviral treatment for HIV/AIDS patients in Vietnam.

Nanoscale strain-hardening of keratin fibres.

A degenerate primer MOB typing (DPMT) method to classify gamma-proteobacterial plasmids in clinical and environmental settings.

Association of adenovirus 36 infection with obesity and metabolic markers in humans: a meta-analysis of observational studies.

Massive Trentepohlia-bloom in a glacier valley of Mt. Gongga, China, and a new variety of Trentepohlia (Chlorophyta).

Association between CD209 -336A/G and -871A/G polymorphisms and susceptibility of tuberculosis: a meta-analysis.

A probabilistic fragment-based protein structure prediction algorithm.

Role of microRNA-182 in posterior uveal melanoma: regulation of tumor development through MITF, BCL2 and cyclin D2.

Correction: MicroRNA-141 Represses HBV Replication by Targeting PPARA

Development and characterization of a new TILLING population of common bread wheat (Triticum aestivum L.).

Endoplasmic reticulum stress stimulates p53 expression through NF-κB activation.

Functional epistatic interaction between rs6046G>A in F7 and rs5355C>T in SELE modifies systolic blood pressure levels.

Skilled Birth Attendants: who is who? A descriptive study of definitions and roles from nine Sub Saharan African countries.

POWRS: position-sensitive motif discovery.

Atrophic cardiac remodeling induced by taurine deficiency in Wistar rats.

Pest-suppression potential of midwestern landscapes under contrasting bioenergy scenarios.

Development of a high-throughput assay for identifying inhibitors of TBK1 and IKKε.

CXCL12/CXCR4 axis triggers the activation of EGF receptor and ERK signaling pathway in CsA-induced proliferation of human trophoblast cells.

Lysyl oxidase polymorphisms and susceptibility to osteosarcoma.

ATP hydrolyzing salivary enzymes of caterpillars suppress plant defenses.

Structural evidence in Plectroniella armata (Rubiaceae) for possible material exchange between domatia and mites.

Correction: Habitat and Scale Shape the Demographic Fate of the Keystone Sea Urchin in Mediterranean Macrophyte Communities.

Number conservation is related to children's prefrontal inhibitory control: an fMRI study of a piagetian task.

Correction: Effect of Chemical Mutagens and Carcinogens on Gene Expression Profiles in Human TK6 Cells

Stimulation of immature lung macrophages with intranasal interferon gamma in a novel neonatal mouse model of respiratory syncytial virus infection.

A model-based method for gene dependency measurement.

Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter.

Correction: Evolution of Eye Morphology and Rhodopsin Expression in the Species Subgroup.

Local oxidative stress expansion through endothelial cells--a key role for gap junction intercellular communication.

One species, three Pleistocene evolutionary histories: phylogeography of the Italian crested newt, Triturus carnifex.

The statistics of urban scaling and their connection to Zipf's law.

Role of plastid transglutaminase in LHCII polyamination and thylakoid electron and proton flow.

Similar evolution of cellular HIV-1 DNA level in darunavir/ritonavir monotherapy versus triple therapy in MONOI-ANRS136 trial over 96 weeks.

Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease.

Differential expression of aquaporins and its diagnostic utility in thyroid cancer.

Gamma band neural synchronization deficits for auditory steady state responses in bipolar disorder patients.

Clinical application of cine-MRI in the visual assessment of mitral regurgitation compared to echocardiography and cardiac catheterization.

GM-CSF priming drives bone marrow-derived macrophages to a pro-inflammatory pattern and downmodulates PGE2 in response to TLR2 ligands.

Acute pain therapy in postanesthesia care unit directed by skin conductance: a randomized controlled trial.

BLM and RMI1 alleviate RPA inhibition of TopoIIIα decatenase activity.

Perivascular-like cells contribute to the stability of the vascular network of osteogenic tissue formed from cell sheet-based constructs.

Low serum urate levels are associated to female gender in multiple sclerosis patients.

Micronutrient requirements for growth and hydrocarbon production in the oil producing green alga Botryococcus braunii (Chlorophyta).

Sustained exendin-4 secretion through gene therapy targeting salivary glands in two different rodent models of obesity/type 2 diabetes.

Are trade-offs among species' ecological interactions scale dependent? A test using pitcher-plant inquiline species.

Security and privacy qualities of medical devices: an analysis of FDA postmarket surveillance.

Selection, phenotyping and identification of acid and hydrogen peroxide producing bacteria from vaginal samples of Canadian and East African women.

Which is a more accurate predictor in colorectal survival analysis? Nine data mining algorithms vs. the TNM staging system.

Correction: Differential Changes in QTc Duration during In-Hospital Haloperidol Use.

Investigating international time trends in the incidence and prevalence of atopic eczema 1990-2010: a systematic review of epidemiological studies.

Construction and characterization of a Streptococcus suis serotype 2 recombinant expressing enhanced green fluorescent protein.

Variability of prefrontal neuronal discharges before and after training in a working memory task.

Epidemiologic and economic burden of influenza in the outpatient setting: a prospective study in a subtropical area of China.

Two new rapid SNP-typing methods for classifying Mycobacterium tuberculosis complex into the main phylogenetic lineages.

Influence of GABA(A) receptor α subunit isoforms on the benzodiazepine binding site.

HILI inhibits TGF-β signaling by interacting with Hsp90 and promoting TβR degradation.

The CXCR3(+)CD56Bright phenotype characterizes a distinct NK cell subset with anti-fibrotic potential that shows dys-regulated activity in hepatitis C.

RBPJ is a novel target for rhabdomyosarcoma therapy.

Interplay between path and speed in decision making by high-dimensional stochastic gene regulatory networks.

Central but not systemic administration of ghrelin induces wakefulness in mice.

Multi-locus variable number of tandem repeat analysis for rapid and accurate typing of virulent multidrug resistant Escherichia coli clones.

NOD1 cooperates with TLR2 to enhance T cell receptor-mediated activation in CD8 T cells.

MicroRNA-122 down-regulation is involved in phenobarbital-mediated activation of the constitutive androstane receptor.

Potential distribution of the Australian native Chloris truncata based on modelling both the successful and failed global introductions.

Complement receptors 1 and 2 in murine antibody responses to IgM-complexed and uncomplexed sheep erythrocytes.

Ageing increases vulnerability to aβ42 toxicity in Drosophila.

Benefits of rebuilding global marine fisheries outweigh costs.

Feasibility and effectiveness of provider initiated HIV testing and counseling of TB suspects in Vizianagaram district, South India.

Bacteroides uniformis CECT 7771 ameliorates metabolic and immunological dysfunction in mice with high-fat-diet induced obesity.

Multi-criteria optimization of regulation in metabolic networks.

Is it benign or is it a Pariah? Empirical evidence for the impact of the common Myna (Acridotheres tristis) on Australian birds.

Promoter DNA methylation regulates murine SUR1 (Abcc8) and SUR2 (Abcc9) expression in HL-1 cardiomyocytes.

Tuning genetic clocks employing DNA binding sites.

Correction: Respective Prognostic Value of Genomic Grade and Histological Proliferation Markers in Early Stage (pN0) Breast Carcinoma

Molecular detection of eukaryotes in a single human stool sample from Senegal.

R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.

Widening educational disparities in premature death rates in twenty six states in the United States, 1993-2007.

Correction: Functional Characterization of Circulating Tumor Cells with a Prostate-Cancer-Specific Microfluidic Device

Chronic kidney disease-induced cardiac fibrosis is ameliorated by reducing circulating levels of a non-dialysable uremic toxin, indoxyl sulfate.

Familiarity with speech affects cortical processing of auditory distance cues and increases acuity.

Iodine nutrition and the prevalence of thyroid disease after salt iodization: a cross-sectional survey in Shanghai, a coastal area in China.

The crystal structures of dystrophin and utrophin spectrin repeats: implications for domain boundaries.

NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast.

Exploring IRES region accessibility by interference of foot-and-mouth disease virus infectivity.

Rac1 activation driven by 14-3-3ζ dimerization promotes prostate cancer cell-matrix interactions, motility and transendothelial migration.

Stavudine toxicity in adult longer-term ART patients in Blantyre, Malawi.

H1-MAPT and the risk for familial essential tremor.

Mating plugs in polyandrous giants: which sex produces them, when, how and why?

Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.

Structure-function analysis of Rny1 in tRNA cleavage and growth inhibition.

Crystal structure of the Sema-PSI extracellular domain of human RON receptor tyrosine kinase.

Multi-parametric relationships between PAM measurements and carbon incorporation, an in situ approach.

Unprocessed viral DNA could be the primary target of the HIV-1 integrase inhibitor raltegravir.

Estrogen regulates hepcidin expression via GPR30-BMP6-dependent signaling in hepatocytes.

Integrating macrophages into organotypic co-cultures: a 3D in vitro model to study tumor-associated macrophages.

Immunocytochemical localization of amines and GABA in the optic lobe of the butterfly, Papilio xuthus.

Thyroid hormone enhances nitric oxide-mediated bacterial clearance and promotes survival after meningococcal infection.

Extreme genetic structure in a small-bodied freshwater fish, the purple spotted gudgeon, Mogurnda adspersa (Eleotridae).

Socioeconomic status and health communication inequalities in Japan: a nationwide cross-sectional survey.

Prevalence of diabetes and pre-diabetes and associated risk factors among tuberculosis patients in India.

Serum fetuin A and chemerin levels correlate with hepatic steatosis and regional adiposity in maintenance hemodialysis patients.

Evaluation of four different systems for extraction of RNA from stool suspensions using MS-2 coliphage as an exogenous control for RT-PCR inhibition.

Lowered risk of nasopharyngeal carcinoma and intake of plant vitamin, fresh fish, green tea and coffee: a case-control study in Taiwan.

Correction: Differential Changes in QTc Duration during In-Hospital Haloperidol Use

The -2518A/G polymorphism in the MCP-1 gene and tuberculosis risk: a meta-analysis.

Correction: Recruiting a New Substrate for Triacylglycerol Synthesis in Plants: The Monoacylglycerol Acyltransferase Pathway.

Reduced APOBEC3H variant anti-viral activities are associated with altered RNA binding activities.

Microarray analysis of the intestinal host response in Giardia duodenalis assemblage E infected calves.

Barriers to HIV testing in Côte d'Ivoire: the role of individual characteristics and testing modalities.

Correction: NKT Cells Stimulated by Long Fatty Acyl Chain Sulfatides Significantly Reduces the Incidence of Type 1 Diabetes in Nonobese Diabetic Mice.

Structural basis of the interaction of a Trypanosoma cruzi surface molecule implicated in oral infection with host cells and gastric mucin.

Structure-function analysis of Rgs1 in Magnaporthe oryzae: role of DEP domains in subcellular targeting.

Serotonin transporter gene (SLC6A4) variations are associated with poor survival in colorectal cancer patients.

Effect of early detection and treatment on malaria related maternal mortality on the north-western border of Thailand 1986-2010.

Analyzing multi-locus plant barcoding datasets with a composition vector method based on adjustable weighted distance.

Low level sequence variant analysis of recombinant proteins: an optimized approach.

Probiotic bacteria regulate intestinal epithelial permeability in experimental ileitis by a TNF-dependent mechanism.

Polymorphisms on 8q24 are associated with lung cancer risk and survival in Han Chinese.

A new body shape index predicts mortality hazard independently of body mass index.

Stability of synchronization clusters and seizurability in temporal lobe epilepsy.

Association between cardiac autonomic function, oxidative stress and inflammatory response in impaired fasting glucose subjects: cross-sectional study.

Room temperature operable autonomously moving bio-microrobot powered by insect dorsal vessel tissue.

Perceptual auditory aftereffects on voice identity using brief vowel stimuli.

Splicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscle.

How do children solve Aesop's Fable?

Correction: Expensive Egos: Narcissistic Males Have Higher Cortisol.

Risk factors for preeclampsia in women from Colombia: a case-control study.

Correction: Prediction of HLA Class II Alleles Using SNPs in an African Population

Measuring parathyroid hormone (PTH) in patients with oxidative stress--do we need a fourth generation parathyroid hormone assay?

Cultural differences in investing in others and in the future: why measuring trust is not enough.

Altered regional homogeneity in the development of minimal hepatic encephalopathy: a resting-state functional MRI study.

Witness response at acute onset of stroke: a qualitative theory-guided study.

Were multiple stressors a 'perfect storm' for northern Gulf of Mexico bottlenose dolphins (Tursiops truncatus) in 2011?

Efficient 2,3-butanediol production from cassava powder by a crop-biomass-utilizer, Enterobacter cloacae subsp. dissolvens SDM.

Functional study of mammalian Neph proteins in Drosophila melanogaster.

Association of genetic variants of melatonin receptor 1B with gestational plasma glucose level and risk of glucose intolerance in pregnant Chinese women.

Genome-wide association mapping and identification of candidate genes for the rumpless and ear-tufted traits of the Araucana chicken.

Non-exchangeability of running vs. other exercise in their association with adiposity, and its implications for public health recommendations.

T7 RNA polymerase functions in vitro without clustering.

Establishment of induced pluripotent stem cells from centenarians for neurodegenerative disease research.

Genome-wide linkage and association analysis identifies major gene loci for guttural pouch tympany in Arabian and German warmblood horses.

Protein inhibitor of activated STAT, PIASy regulates α-smooth muscle actin expression by interacting with E12 in mesangial cells.

Hunter-gatherer energetics and human obesity.

Mouse transgenesis in a single locus with independent regulation for multiple fluorophores.

Geometrical microfeature cues for directing tubulogenesis of endothelial cells.

Niche tracking and rapid establishment of distributional equilibrium in the house sparrow show potential responsiveness of species to climate change.

Methylomic analysis identifies frequent DNA methylation of zinc finger protein 582 (ZNF582) in cervical neoplasms.

Effect of hearing aids on auditory function in infants with perinatal brain injury and severe hearing loss.

Upregulation of the coagulation factor VII gene during glucose deprivation is mediated by activating transcription factor 4.

Development of a charting method to monitor the individual performance of surgeons at the beginning of their career.

The effect of monthly sulfadoxine-pyrimethamine, alone or with azithromycin, on PCR-diagnosed malaria at delivery: a randomized controlled trial.

Correction: A Powerful Test of Parent-of-Origin Effects for Quantitative Traits Using Haplotypes.

Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS.

Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment.

The species identity of the widely cultivated Ganoderma, 'G. lucidum' (Ling-zhi), in China.

Ultramarine, a chromoprotein acceptor for Förster resonance energy transfer.

Disentangling depression and distress networks in the tinnitus brain.

Passerine birds breeding under chronic noise experience reduced fitness.

Comparing the MicroRNA spectrum between serum and plasma.

Constitutive gene expression in monocytes from chronic HIV-1 infection overlaps with acute Toll-like receptor induced monocyte activation profiles.

Regulation of nuclear factor κB (NF-κB) transcriptional activity via p65 acetylation by the chaperonin containing TCP1 (CCT).

Global analysis of the small RNA transcriptome in different ploidies and genomic combinations of a vertebrate complex--the Squalius alburnoides.

Thermotaxis of human sperm cells in extraordinarily shallow temperature gradients over a wide range.

Correction: Prediction of HLA Class II Alleles Using SNPs in an African Population.

Evaluation of a single procedure allowing the isolation of enteropathogenic Yersinia along with other bacterial enteropathogens from human stools.

Correction: Gender, Obesity and Repeated Elevation of C-Reactive Protein: Data from the CARDIA Cohort.

HLA associations in classical Hodgkin lymphoma: EBV status matters.

Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma.

New strategy for rapid diagnosis and characterization of fungal infections: the example of corneal scrapings.

Correction: Extensions of MADM (Mosaic Analysis with Double Markers) in Mice

Leptospirosis outbreak following severe flooding: a rapid assessment and mass prophylaxis campaign; Guyana, January-February 2005.

Genetic determinants for body iron store and type 2 diabetes risk in US men and women.

Long chain polyunsaturated fatty acids alter oxytocin signaling and receptor density in cultured pregnant human myometrial smooth muscle cells.

Prediction and analysis of the protein interactome in Pseudomonas aeruginosa to enable network-based drug target selection.

Comprehensive mutation analysis in colorectal flat adenomas.

Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets.

Correction: Ancient DNA from Hunter-Gatherer and Farmer Groups from Northern Spain Supports a Random Dispersion Model for the Neolithic Expansion into Europe

CT scan screening for lung cancer: risk factors for nodules and malignancy in a high-risk urban cohort.

VAPC, an human endogenous inhibitor for hepatitis C virus (HCV) infection, is intrinsically unstructured but forms a "fuzzy complex" with HCV NS5B.

Learning impairment in honey bees caused by agricultural spray adjuvants.

Genotyping of Plasmodium vivax reveals both short and long latency relapse patterns in Kolkata.

Low concentration of silver nanoparticles not only enhances the activity of horseradish peroxidase but alter the structure also.

The transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties.

Dimerization and heme binding are conserved in amphibian and starfish homologues of the microRNA processing protein DGCR8.

Coevolutionary constraints? The environment alters tripartite interaction traits in a legume.

Constitutive phosphorylation of interferon receptor A-associated signaling proteins in systemic lupus erythematosus.

T cell subsets in HIV infected patients after successful combination antiretroviral therapy: impact on survival after 12 years.

IRF7 regulates TLR2-mediated activation of splenic CD11c(hi) dendritic cells.

Correlates of reported and recorded time spent in physical activity in working adults: results from the commuting and health in Cambridge study.

Do adolescent idiopathic scoliosis (AIS) neglect proprioceptive information in sensory integration of postural control?

Fc-epsilon-RI, the high affinity IgE-receptor, is robustly expressed in the upper gastrointestinal tract and modulated by mucosal inflammation.

Roflumilast-N-oxide induces surfactant protein expression in human alveolar epithelial cells type II.

Common protein biomarkers assessed by reverse phase protein arrays show considerable intratumoral heterogeneity in breast cancer tissues.

"Of sheep and men": earliest direct evidence of caprine domestication in southern Africa at Leopard Cave (Erongo, Namibia).

C/EBP homologous protein (CHOP) deficiency aggravates hippocampal cell apoptosis and impairs memory performance.

Computerized cognitive training with older adults: a systematic review.

Where are all the fish: potential of biogeographical maps to project current and future distribution patterns of freshwater species.

GIP-overexpressing mice demonstrate reduced diet-induced obesity and steatosis, and improved glucose homeostasis.

Mapping MKP-3/FOXO1 interaction and evaluating the effect on gluconeogenesis.

Heat induced capsid disassembly and DNA release of bacteriophage λ.

IL-21 regulates the differentiation of a human γδ T cell subset equipped with B cell helper activity.

Fast recruitment of recurrent inhibition in the cat visual cortex.

Mannose-binding lectin deficiency is associated with myocardial infarction: the HUNT2 study in Norway.

Failure of long-term memory formation in juvenile snails is determined by acetylation status of histone H3 and can be improved by NaB treatment.

Phylogenetic position and replication kinetics of Heliothis virescens ascovirus 3h (HvAV-3h) isolated from Spodoptera exigua.

Intranasal vaccination with murabutide enhances humoral and mucosal immune responses to a virus-like particle vaccine.

Dahl (S x R) congenic strain analysis confirms and defines a chromosome 5 female-specific blood pressure quantitative trait locus to <7 Mbp.

FGF21 promotes metabolic homeostasis via white adipose and leptin in mice.

Unique alterations of an ultraconserved non-coding element in the 3'UTR of ZIC2 in holoprosencephaly.

Design and characterization of auxotrophy-based amino acid biosensors.

Estimating the per-contact probability of infection by highly pathogenic avian influenza (H7N7) virus during the 2003 epidemic in The Netherlands.

Correction: Mind Bomb-1 in Dendritic Cells Is Specifically Required for Notch-mediated T Helper Type 2 Differentiation

Increased microparticle production and impaired microvascular endothelial function in aldosterone-salt-treated rats: protective effects of polyphenols.

Endothelin-1 in paraventricular nucleus modulates cardiac sympathetic afferent reflex and sympathetic activity in rats.

Sequencing of seven haloarchaeal genomes reveals patterns of genomic flux.

Selection signature analysis implicates the PC1/PCSK1 region for chicken abdominal fat content.

Antibodies to the α1-adrenergic receptor cause vascular impairments in rat brain as demonstrated by magnetic resonance angiography.

Growth of mouse oocytes to maturity from premeiotic germ cells in vitro.

Dysregulation of cytokine response in Canadian First Nations communities: is there an association with persistent organic pollutant levels?

Satiating capacity and post-prandial relationships between appetite parameters and gut-peptide concentrations with solid and liquefied carbohydrate.

Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells.

Germ cell development in the scleractinian coral Euphyllia ancora (Cnidaria, Anthozoa).

Strong spatial influence on colonization rates in a pioneer zooplankton metacommunity.

NFAT5 is activated by hypoxia: role in ischemia and reperfusion in the rat kidney.

Validation of the β-amy1 transcription profiling assay and selection of reference genes suited for a RT-qPCR assay in developing barley caryopsis.

Involvement of host stroma cells and tissue fibrosis in pancreatic tumor development in transgenic mice.

Breed-dependent transcriptional regulation of 5'-untranslated GR (NR3C1) exon 1 mRNA variants in the liver of newborn piglets.

Systematic functional characterization of cytochrome P450 2E1 promoter variants in the Chinese Han population.

Empirical validation of pooled whole genome population re-sequencing in Drosophila melanogaster.

Water-pipe smoking and metabolic syndrome: a population-based study.

Transcriptional regulation of PES1 expression by c-Jun in colon cancer.

Molecular dynamics of a thermostable multicopper oxidase from Thermus thermophilus HB27: structural differences between the apo and holo forms.

3q26 amplification is an effective negative triage test for LSIL: a historical prospective study.

Differential effect of growth factors on invasion and proliferation of endocrine resistant breast cancer cells.

Oral antimicrobial rinse to reduce mycobacterial culture contamination among tuberculosis suspects in Uganda: a prospective study.

A novel survival-based tissue microarray of pancreatic cancer validates MUC1 and mesothelin as biomarkers.

Mechanisms of GnRH-induced extracellular signal-regulated kinase nuclear localization.

Effect of genetic variation in STXBP5 and STX2 on von Willebrand factor and bleeding phenotype in type 1 von Willebrand disease patients.

Time-resolved influences of functional DAT1 and COMT variants on visual perception and post-processing.

Partial regulatory T cell depletion prior to schistosomiasis vaccination does not enhance the protection.

The power laws of violence against women: rescaling research and policies.

Persistence, spatial distribution and implications for progression detection of blind parts of the visual field in glaucoma: a clinical cohort study.

An improved genetically encoded red fluorescent Ca2+ indicator for detecting optically evoked action potentials.

Single-item screening for agoraphobic symptoms: validation of a web-based audiovisual screening instrument.

Glycerol monolaurate antibacterial activity in broth and biofilm cultures.

Acute knockdown of uncoupling protein-2 increases uncoupling via the adenine nucleotide transporter and decreases oxidative stress in diabetic kidneys.

Fis is essential for the stability of linear plasmid pBSSB1 and affects the motility of Salmonella enterica serovar Typhi.

Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.

Dopamine genes (DRD2/ANKK1-TaqA1 and DRD4-7R) and executive function: their interaction with obesity.

Pharyngeal polysaccharide deacetylases affect development in the nematode C. elegans and deacetylate chitin in vitro.

Rapid nitration of adipocyte phosphoenolpyruvate carboxykinase by leptin reduces glyceroneogenesis and induces fatty acid release.

MC-12, an annexin A1-based peptide, is effective in the treatment of experimental colitis.

Naturally-occurring genetic variants in human DC-SIGN increase HIV-1 capture, cell-transfer and risk of mother-to-child transmission.

A pseudo-tRNA modulates antibiotic resistance in Bacillus cereus.

Regulation of the cyanobacterial CO2-concentrating mechanism involves internal sensing of NADP+ and α-ketogutarate levels by transcription factor CcmR.

Serum 25-hydroxyvitamin D3 and D2 and non-clinical psychotic experiences in childhood.

Structural heterogeneity of terminal glycans in Campylobacter jejuni lipooligosaccharides.

Modulation of MicroRNA-194 and cell migration by HER2-targeting trastuzumab in breast cancer.

Percutaneous disc decompression with nucleoplasty-volumetry of the nucleus pulposus using ultrahigh-field MRI.

Distinct innate immune gene expression profiles in non-melanoma skin cancer of immunocompetent and immunosuppressed patients.

The effect of HLA polymorphisms on the recognition of Gag epitopes in HIV-1 CRF01_AE infection.

Characterization and whole genome analysis of human papillomavirus type 16 e1-1374^63nt variants.

Prospective validation of ELF test in comparison with Fibroscan and FibroTest to predict liver fibrosis in Asian subjects with chronic hepatitis B.

The loss of metabolic control on alcohol drinking in heavy drinking alcohol-dependent subjects.

Reevaluation of ANS binding to human and bovine serum albumins: key role of equilibrium microdialysis in ligand - receptor binding characterization.

Expression of mast cell proteases correlates with mast cell maturation and angiogenesis during tumor progression.

Recently emerged swine influenza A virus (H2N3) causes severe pneumonia in Cynomolgus macaques.

Rapid increase in prevalence of male circumcision in rural Tanzania in the absence of a promotional campaign.

Biologging, remotely-sensed oceanography and the continuous plankton recorder reveal the environmental determinants of a seabird wintering hotspot.

Insertion of short amino-functionalized single-walled carbon nanotubes into phospholipid bilayer occurs by passive diffusion.

Testing for the effects and consequences of mid paleogene climate change on insect herbivory.

Robustness elasticity in complex networks.

Calcium binding promotes prion protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure.

Correction: Evolutionary Responses to a Constructed Niche: Ancient Mesoamericans as a Model of Gene-Culture Coevolution

Adenovirus-36 is associated with obesity in children and adults in Sweden as determined by rapid ELISA.

Cell recruitment and cytokines in skin mice sensitized with the vaccine adjuvants: saponin, incomplete Freund's adjuvant, and monophosphoryl lipid A.

Low functional β-diversity despite high taxonomic β-diversity among tropical estuarine fish communities.

Haploinsufficiency for translation elongation factor eEF1A2 in aged mouse muscle and neurons is compatible with normal function.

Evaluation for fasting and 2-hour glucose and HbA1c for diagnosing diabetes based on prevalence of retinopathy in a Chinese population.

Challenges of loss to follow-up in tuberculosis research.

Body iron stores and heme-iron intake in relation to risk of type 2 diabetes: a systematic review and meta-analysis.

Oscillation in cycle length induces transient discordant and steady-state concordant alternans in the heart.

Induction of RAGE shedding by activation of G protein-coupled receptors.

Serological evidence of Ebola virus infection in Indonesian orangutans.

Modulatory role of PYY in transport and metabolism of cholesterol in intestinal epithelial cells.

Schisandrin B attenuates cancer invasion and metastasis via inhibiting epithelial-mesenchymal transition.

Hexokinase 2, glycogen synthase and phosphorylase play a key role in muscle glycogen supercompensation.

Prediction of carbohydrate binding sites on protein surfaces with 3-dimensional probability density distributions of interacting atoms.

DSP-PP precursor protein cleavage by tolloid-related-1 protein and by bone morphogenetic protein-1.

The evolving proteome of a complex extracellular matrix, the Oikopleura house.

Opposite effects of methanandamide on lipopolysaccharide-induced prostaglandin E2 and F2α synthesis in uterine explants from pregnant mice.

PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.

Diffuse coevolution between two Epicephala species (Gracillariidae) and two Breynia species (Phyllanthaceae).

Identification and characterization of tropomyosin 3 associated with granulin-epithelin precursor in human hepatocellular carcinoma.

Electric field detection in sawfish and shovelnose rays.

Characterization of HIV-specific CD4+ T cell responses against peptides selected with broad population and pathogen coverage.

A novel property of DNA - as a bioflotation reagent in mineral processing.

Water level flux in household containers in Vietnam--a key determinant of Aedes aegypti population dynamics.

Correction: RNA-Binding Protein Musashi1 Modulates Glioma Cell Growth through the Post-Transcriptional Regulation of Notch and PI Kinase/Akt Signaling Pathways.

C-terminal substitution of HBV core proteins with those from DHBV reveals that arginine-rich 167RRRSQSPRR175 domain is critical for HBV replication.

Associations of CFH polymorphisms and CFHR1-CFHR3 deletion with blood pressure and hypertension in Chinese population.

Retraction: Transcriptional repressor Gfi1 integrates cytokine-receptor signals controlling B-cell differentiation.

The attentional window modulates capture by audiovisual events.

How academics face the world: a study of 5829 homepage pictures.

Arterial structure and function in mild primary hyperparathyroidism is not directly related to parathyroid hormone, calcium, or vitamin D.

Correction: Micro-Raman Spectroscopy of Silver Nanoparticle Induced Stress on Optically-Trapped Stem Cells.

Correction: The Structure of Mutations and the Evolution of Cooperation.

Chinese minimally invasive percutaneous nephrolithotomy for intrarenal stones in patients with solitary kidney: a single-center experience.

Hypoglycemia in non-diabetic in-patients: clinical or criminal?

Correction: National Prevalence and Trends of HIV Transmitted Drug Resistance in Mexico

Discovering communities through friendship.

Tenofovir use and renal insufficiency among pregnant and general adult population of HIV-infected, ART-naïve individuals in Lilongwe, Malawi.

Correction: Functional Characterization of Circulating Tumor Cells with a Prostate-Cancer-Specific Microfluidic Device.

Risk behaviors for reproductive tract infection in women who have sex with women in Beijing, China.

Reduced intestinal tumorigenesis in APCmin mice lacking melanin-concentrating hormone.

Molecular and microscopic analysis of bacteria and viruses in exhaled breath collected using a simple impaction and condensing method.

Correction: Bmi-1 Absence Causes Premature Brain Degeneration.

A comparative analysis of polyfunctional T cells and secreted cytokines induced by Bacille Calmette-Guérin immunisation in children and adults.

Gq/11-mediated signaling and hypertrophy in mice with cardiac-specific transgenic expression of regulator of G-protein signaling 2.

Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.

Ectopically expressed perforin-1 is proapoptotic in tumor cell lines by increasing caspase-3 activity and the nuclear translocation of cytochrome C.

A neurotoxic phospholipase A2 impairs yeast amphiphysin activity and reduces endocytosis.

Recombinant lipidated HPV E7 induces a Th-1-biased immune response and protective immunity against cervical cancer in a mouse model.

First Epigravettian ceramic figurines from Europe (Vela Spila, Croatia).

Functions of nonmuscle myosin II in assembly of the cellular contractile system.

Ferritin blocks inhibitory effects of two-chain high molecular weight kininogen (HKa) on adhesion and survival signaling in endothelial cells.

Gene expression of Mycobacterium tuberculosis putative transcription factors whiB1-7 in redox environments.

Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials.

Mercury-selenium relationships in liver of Guiana dolphin: the possible role of Kupffer cells in the detoxification process by tiemannite formation.

Design and construction of "synthetic species".

Intergenerational predictors of birth weight in the Philippines: correlations with mother's and father's birth weight and test of maternal constraint.

Local loperamide injection reduces mechanosensitivity of rat cutaneous, nociceptive C-fibers.

H2O2 production downstream of FLT3 is mediated by p22phox in the endoplasmic reticulum and is required for STAT5 signalling.

Role of heat-stable enterotoxins in the induction of early immune responses in piglets after infection with enterotoxigenic Escherichia coli.

Glucose is a pH-dependent motor for sperm beat frequency during early activation.

Identification of pathway deregulation--gene expression based analysis of consistent signal transduction.

Psyllium supplementation in adolescents improves fat distribution & lipid profile: a randomized, participant-blinded, placebo-controlled, crossover trial.

Correlates of in-hospital deaths among hospitalizations with pulmonary embolism: findings from the 2001-2008 National Hospital Discharge Survey.

Effect of dust and anthropogenic aerosols on columnar aerosol optical properties over Darjeeling (2200 m asl), eastern Himalayas, India.

Effect of vitamin D supplementation on Mycobacterium tuberculosis-induced innate immune responses in a Canadian Dené First Nations cohort.

Scheduled daily mating induces circadian anticipatory activity rhythms in the male rat.

Staphylococcus aureus isolates encode variant staphylococcal enterotoxin B proteins that are diverse in superantigenicity and lethality.

Posttraumatic stress symptoms after exposure to two fire disasters: comparative study.

Trait and state positive emotional experience in schizophrenia: a meta-analysis.

Self-love or other-love? Explicit other-preference but implicit self-preference.

Energy metabolism during repeated sets of leg press exercise leading to failure or not.

Prenatal stress and peripubertal stimulation of the endocannabinoid system differentially regulate emotional responses and brain metabolism in mice.

Effects of elevated CO2 and temperature on yield and fruit quality of strawberry (Fragaria × ananassa Duch.) at two levels of nitrogen application.

Childhood growth, IQ and education as predictors of white blood cell telomere length at age 49-51 years: the Newcastle Thousand Families Study.

Correction: Novel, Real-Time Cell Analysis for Measuring Viral Cytopathogenesis and the Efficacy of Neutralizing Antibodies to the 2009 Influenza A (H1N1) Virus

96 Week follow-up of HIV-infected patients in rescue with raltegravir plus optimized backbone regimens: a multicentre Italian experience.

Correction: Temporal Dissection of K-rasG12D Mutant In Vitro and In Vivo Using a Regulatable K-rasG12D Mouse Allele

Enhancement of implant osseointegration by high-frequency low-magnitude loading.

Higher memory responses in HIV-infected and kidney transplanted patients than in healthy subjects following priming with the pandemic vaccine.

Hypoxia changes the expression of the epidermal growth factor (EGF) system in human hearts and cultured cardiomyocytes.

Identification of hsa-miR-335 as a prognostic signature in gastric cancer.

Effect of substrate stiffness on early mouse embryo development.

De novo generation of cells within human nurse macrophages and consequences following HIV-1 infection.

Inflammation drives dysbiosis and bacterial invasion in murine models of ileal Crohn's disease.

Concordance of gene expression and functional correlation patterns across the NCI-60 cell lines and the Cancer Genome Atlas glioblastoma samples.

Year: 2011, Volume: 7

Year: 2011, Volume: 6

Year: 2010, Volume: 5

Year: 2009, Volume: 4

Year: 2008, Volume: 3

Year: 2007, Volume: 2

In vivo determination of mouse olfactory mucus cation concentrations in normal and inflammatory states.

Content Provider	Directory of Open Access Journals (DOAJ)
Author	Senthil Selvaraj Kevin Liu Alan M. Robinson Victoria A. Epstein David B. Conley Robert C. Kern Claus-Peter Richter
Abstract	OBJECTIVE: Olfaction is impaired in chronic rhinosinusitis (CRS). The study has two aims: (1) to determine whether changes in cation concentration occur in the olfactory mucus of mice with CRS, which may affect chemo-electrical transduction, (2) and to examine whether these alterations are physiologically significant in humans. STUDY DESIGN: Animal study in mice and translational study in humans. METHODS: Inflammation was induced by sensitization and chronic exposure of 16 C57BL/6 mice to Aspergillus fumigatus. The control group included 16 untreated mice. Ion-selective microelectrodes were used to measure free cation concentrations in the olfactory mucus of 8 mice from each treatment group, while the remaining mice were sacrificed for histology. To validate the findings in the animal model, olfactory threshold was measured in 11 healthy human participants using Sniffin' Sticks before and after nasal irrigation with solutions that were composed of either of the cation concentrations. RESULTS: In 8 mice, olfactory mucus of chronically inflamed mice had lower [Na(+)] (84.8±4.45 mM versus 93.73±3.06 mM, p = 0.02), and higher [K(+)] (7.2±0.65 mM versus 5.7±0.20 mM, p = 0.04) than controls. No difference existed in [Ca(2+)] (0.50±0.12 mM versus 0.54±0.06 mM, p = 0.39). In humans, rinsing with solutions replicating ion concentrations of the mouse mucosa with chronic inflammation caused a significant elevation in the median olfactory threshold (9.0 to 4.8, p = 0.003) but not with the control solution (8.3 to 7.8, p = 0.75). CONCLUSION: Chronic inflammation elevates potassium and lowers sodium ion concentration in mice olfactory mucus. Nasal irrigation with a corresponding solution induced olfactory threshold shift in humans.
e-ISSN	19326203
DOI	10.1371/journal.pone.0039600
Journal	PLoS ONE
Issue Number	7
Volume Number	7
Language	English
Publisher	Public Library of Science (PLoS)
Publisher Date	2012-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Medicine Science
Content Type	Text
Resource Type	Article

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