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Novel nucleophilic heterocyclic carbene mediated stereoselective conjugate addition of enals to nitrostyrenes via homoenolate
| Content Provider | CSIR - National Institute for Interdisciplinary Science and Technology (NIIScT) |
|---|---|
| Author | Nair, G. Vijay Sinu, C. R. Beneesh, P. B. Varghese, V. Jose, Anu Suresh, E. |
| Abstract | A stereoselective Michael addition of homoenolate, generated from enals by nucleophilic heterocyclic carbene (NHC) catalysis, to beta-nitrostyrenes is reported for the first time. The products of this reaction obtained in good yields are of potential value in the synthesis of a variety of acyclic and heterocyclic compounds. |
| Starting Page | 5570 |
| Ending Page | 5573 |
| Page Count | 3 |
| ISSN | 15237060 |
| Journal | Organic Letters |
| Volume Number | 11 |
| Issue Number | 24 |
| Language | English |
| Publisher | American Chemical Society |
| Publisher Date | 2009-12-17 |
| Access Restriction | Open |
| Subject Keyword | Bond forming reactions Gamma butyrolactones Michael additions Enantioselective synthesis Carbonyl compounds Silyl ether Nitroalkenes |
| Content Type | Text |
| Resource Type | Article |
| Subject | Biochemistry Organic Chemistry Physical and Theoretical Chemistry |