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Pulmonary resection for patients with multidrug-resistant tuberculosis: systematic review and meta-analysis
| Content Provider | CiteSeerX |
|---|---|
| Author | Li, Ling Jiang, Rui-Hua Xu, Hong-Bin |
| Abstract | Objectives: Multidrug-resistant tuberculosis (MDR-TB) has become an emerging global public health crisis. Several studies have suggested that pulmonary resection has efficacy in the treatment of MDR-TB. A systematic review of the available therapeutic studies was conducted to determine the treatment outcome among patients with MDR-TB who underwent pulmonary resection. Methods: To evaluate pulmonary resection for MDR-TB, a random-effect meta-analysis of the available studies was used to assess the overall treatment outcome. Subgroup analyses were also conducted by separating studies based on each characteristic independently. Results: After screening 4996 articles, 15 clinical reports with a mean of 63 patients per report met the inclusion criteria. Analysis of the studies showed that the estimated pooled treatment success rate of pulmon-ary resection for patients with MDR-TB was 84 % [95 % confidence interval (CI) 78%–89%]. The rates of failure, |
| File Format | |
| Access Restriction | Open |
| Content Type | Text |
