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the Multi-Ethnic Study of Atherosclerosis (MESA). Materials and Methods Materials and Methods are available in the online-only Data
| Content Provider | CiteSeerX |
|---|---|
| Abstract | Arterial flow-mediated dilation (FMD) is an indirect measurement of endothelial nitric oxide (NO) release.1 Impaired FMD represents systemic vascular endothelial dys-function that is commonly associated with cardiovascular disease (CVD).2,3 In addition, the association of FMD with CVD is evidenced by its ability to predict future CVD events in population-based studies.4,5 Endothelial dysfunction, defined by impaired FMD, has been reported in patients with atrial fibrillation (AF).6,7 Also, abnormalities in NO signaling have been implicated in atrial ectopy near the pulmonary veins.8,9 These findings suggest a potential role for endothelial dysfunction in the development of AF. However, data from population-based studies to sup-port this claim are lacking. The purpose of this study was to examine the association of brachial FMD with incident AF in |
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| Access Restriction | Open |
| Content Type | Text |