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Nonlinear Optical Microscopy of Hematoxylin and Eosin Stained Histological Sections
| Content Provider | CiteSeerX |
|---|---|
| Author | Adur, Javier Bianchi, Mariana Pelegati, Vitor B. Viale, Silvia Izaguirre, María F. Carvalho, Es F. Cesar, Carlos L. Casco, Víctor H. |
| Abstract | Combined multimodal nonlinear optical (NLO) microscopies were used to detect and quantify morphological changes associated with stroma and epithelial transformation in colon cancer. Our findings provide complementary information about tissue microstructure, displaying distinctive patterns between normal and malignant human colon. Additionally, we have demonstrated the usefulness of using fixed tissues for the disease diagnostic and prognostic. The present work pro-vides a framework for using NLO techniques as a clinical diagnostic tool for human colon cancer. NLO metrics could be applied to other disorders, which are characterized by abnormal cell proli- |
| File Format | |
| Access Restriction | Open |
| Content Type | Text |