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Application of Multilayer Collagen/HA Scaffold in Cartilage Tissue Engineering
| Content Provider | CiteSeerX |
|---|---|
| Author | Wu, Gang Wang, Yingjun Lu, Huading Chen, Xiaofeng Ning, Chengyun Zhao, Naru |
| Abstract | Abstract. In this article, a multilayer tissue engineering scaffold has been fabricated. The uppermost layer is consisted by the collagen and the downmost layer is consisted by the collagen/hydroxyapatide. Between the two layers, there have several continues changed collagen/HA layers at different ratio. These gradient scaffolds have been made by the freeze dried method. The morphology of the multiphase scaffold has been observed by the SEM. The chondrocytes from New Zealand rabbit knee joint were separated, harvested and cultured on the top layer of the scaffold. The histological and the immunohis-tochemical testing show that the chondrocytes keep its normal type in the 2 culture weeks. |
| File Format | |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |