Loading...
Please wait, while we are loading the content...
Cell Stress Induces Upregulation of Osteopontin via the ERK Pathway in Type II Alveolar Epithelial Cells
| Content Provider | CiteSeerX |
|---|---|
| Author | Kato, Aki Okura, Takafumi Hamada, Chizuru Miyoshi, Seigo Katayama, Hitoshi Higaki, Jitsuo Ito, Ryoji Plos, Epithelial Cells |
| Abstract | Osteopontin (OPN) is a multifunctional protein that plays important roles in cell growth, differentiation, migration and tissue fibrosis. In human idiopathic pulmonary fibrosis and murine bleomycin-induced lung fibrosis, OPN is upregulated in type II alveolar epithelial cells (AEC II). However, the mechanism of OPN induction in AEC II is not fully understood. In this study, we |
| File Format | |
| Access Restriction | Open |
| Content Type | Text |