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Generating fiber crossing phantoms out of experimental DWIs
| Content Provider | CiteSeerX |
|---|---|
| Author | Vos, Frans Akkerman, Erik Grimbergen, Kees Caan, Matthan Khedoe, Ganesh Vries, Anne Willem De Vliet, Lucas Van |
| Abstract | Abstract. In Diffusion Tensor Imaging (DTI), differently oriented fiber bundles inside one voxel are incorrectly modeled by a single tensor. High Angular Resolution Diffusion Imaging (HARDI) aims at using more complex models, such as a two-tensor model, for estimating two fiber bundles. We propose a new method for creating experimental phantom data of fiber crossings, by mixing the DWI-signals from high FA-regions with different orientation. The properties of these experimental phantoms approach the conditions of real data. These phantoms can thus serve as a ‘ground truth ’ in validating crossing reconstruction algorithms. The angular resolution of a dual tensor model is determined using series of crossings, generated under different angles. An angular resolution of 0.6π was found in data scanned with a diffusion weighting parameter b=1000 s/mm 2. This resolution did not change significantly in experiments with b=3000 and 5000 s/mm 2, keeping the scanning time constant. 1 |
| File Format | |
| Access Restriction | Open |
| Subject Keyword | High Fa-regions Single Tensor Angular Resolution Dual Tensor Model Experimental Dwis Fiber Bundle Experimental Phantom Data Two-tensor Model Fiber Crossing High Angular Resolution Diffusion Imaging Scanning Time Experimental Phantom |
| Content Type | Text |
| Resource Type | Article |
