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Tissue Pulsatility Imaging of Cerebral Vasoreactivity during
| Content Provider | CiteSeerX |
|---|---|
| Author | Kucewicz, John C. Dunmire, Barbrina Giardino, Nicholas D. Leotta, Daniel F. Dager, Stephen R. Beach, Kirk W. |
| Abstract | Tissue Pulsatility Imaging (TPI) is an ultrasonic technique that is being developed at the University of Washington to measure tissue displacement or strain due to blood flow over the cardiac and respiratory cycles. This technique is based in principle on plethysmography, an older non-ultrasound technology for measuring expansion of a whole limb or body part due to perfusion. TPI adapts tissue Doppler signal processing methods to measure the “plethysmographic ” signal from hundreds or thousands of sample volumes in an ultrasound image plane. This paper presents a feasibility study to determine if TPI can be used to assess cerebral vasoreactivity. Ultrasound data were collected transcranially through the temporal acoustic window from four subjects before, during, and after voluntary hyperventilation. In each subject, decreases in tissue pulsatility during hyperventilation were observed that were statistically correlated with the subject’s end-tidal CO2 measurements. Keywords ultrasound; tissue pulsatility imaging; brain imaging; tissue Doppler imaging; hyperventilation; hypocapnia; cerebral vasoreactivity |
| File Format | |
| Access Restriction | Open |
| Subject Keyword | Cerebral Vasoreactivity Tissue Pulsatility Imaging Subject End-tidal Co2 Measurement Voluntary Hyperventilation Plethysmographic Signal Brain Imaging Whole Limb Non-ultrasound Technology Tissue Pulsatility Body Part Respiratory Cycle Tissue Doppler Signal Processing Method Feasibility Study Ultrasound Image Plane Doppler Imaging Pulsatility Imaging Ultrasonic Technique Temporal Acoustic Window Keywords Ultrasound Sample Volume |
| Content Type | Text |
| Resource Type | Article |
