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Additional file 1 sympathetic nervous system and chronic fatigue syndrome.
| Content Provider | CiteSeerX |
|---|---|
| Abstract | In literature on chronic fatigue syndrome (CFS), there seems to be no consensus on whether this disorder is characterized by hyperfunction [121], normalcy [122] or hypofunction [123] of the sympathetic nervous system (SNS), although it is generally accepted that CFS patients tend to have some kind of dysfunction of the autonomic nervous system [124,125]. This dysautonomia may present as a combination of abnormally high and low test values obtained from various assays of the SNS and parasympathetic nervous system functions [125,126]. It is known that increased activity of the SNS typically results in vasoconstriction in most tissues (except for brain parenchyma [127] and skeletal muscle), elevated blood pressure, increased heart rate, and an elevated plasma level of norepinephrine (one of the major sympathetic neurotransmitters) [128-130]. Reduced activity of the SNS will usually have the opposite effects [131]. Below is a brief overview of literature on the status of these physiological variables in CFS: a) Estimates of baseline vascular tone in CFS patients, as measured by total peripheral resistance (mean arterial pressure divided by cardiac output), suggest that there may be a trend toward greater peripheral vasoconstriction associated with CFS [132-134]. On the |
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| Access Restriction | Open |
| Subject Keyword | Chronic Fatigue Syndrome Sympathetic Nervous System Additional File Cf Patient Peripheral Vasoconstriction Increased Heart Rate Increased Activity Brain Parenchyma Blood Pressure Baseline Vascular Tone Total Peripheral Resistance Various Assay Mean Arterial Pressure Physiological Variable Autonomic Nervous System Skeletal Muscle Parasympathetic Nervous System Function Elevated Plasma Level Cf 132-134 Major Sympathetic Neurotransmitter Cardiac Output Opposite Effect Brief Overview Low Test Value |
| Content Type | Text |
