Loading...
Please wait, while we are loading the content...
Similar Documents
Culture of fetal cells from maternal blood for prenatal diagnosis.
| Content Provider | CiteSeerX |
|---|---|
| Author | Gussin, Heâleáne A. Elicha Elias, Sherman |
| Abstract | The isolation and analysis of fetal cells from maternal blood would allow non-invasive prenatal genetic screening and diagnosis. Over the past decade, progress has been made towards this goal using various enrichment strategies and analysis by ¯uorescence in-situ hybridization with chromosome-speci®c probes and PCR. One method that is currently being explored involves culturing fetal cells. Developing conditions which allow the number of fetal-derived cells to expand in culture and the number of maternally derived cells to be suppressed in culture may lead to a new selection process for obtaining fetal cells. Culturing of fetal cells from maternal blood could make possible conventional metaphase analysis of fetal cells for diagnosis of chromosomal abnormalities. |
| File Format | |
| Access Restriction | Open |
| Subject Keyword | Fetal Cell Maternal Blood Prenatal Diagnosis Fetal-derived Cell New Selection Process Chromosomal Abnormality Various Enrichment Strategy Non-invasive Prenatal Genetic Screening Possible Conventional Metaphase Analysis Uorescence In-situ Hybridization Chromosome-speci Probe Past Decade |
| Content Type | Text |
