Loading...
Please wait, while we are loading the content...
A Comparison of the Diagnostic Accuracy of 18F-FDG PET and CT in the Characterization of Solitary Pulmonary Nodules
| Content Provider | CiteSeerX |
|---|---|
| Author | Coleman, R. Edward Kymes, Steven M. Segall, George Thet, Lyn A. Lowe, Val J. Gould, Michael Fletcher, James W. Snap, Va Marn, Charles Lee, Kelvin Alazraki, Naomi |
| Abstract | CT and PET are widely used to characterize solitary pulmonary nodules (SPNs). However, most CT accuracy studies have been performed with outdated technology and methods, and previous PET studies have been limited by small sample sizes and incom-plete masking. Our objective was to compare CT and PET accu-racy in veterans with SPN.Methods:Between January 1999 and June 2001, we recruited 532 participants with SPNs newly diag-nosed on radiography and untreated. The SPNs were 7–30 mm. All patients underwent 18F-FDG PET and CT. A masked panel of 3 PET and 3 CT experts rated the studies on a 5-point scale. SPN tissue diagnosis or 2-y follow-up established the final diagnosis. Results: A definitive diagnosis was established for 344 partici-pants. The prevalence of malignancy was 53%. The average size was 16 mm. Likelihood ratios (LRs) for PET and CT results for combined ratings of either definitely benign (33 % and 9% |
| File Format | |
| Access Restriction | Open |
| Subject Keyword | Final Diagnosis Previous Pet Study Solitary Pulmonary Nodule 5-point Scale Ct Result Incom-plete Masking Ct Accuracy Study Masked Panel Combined Rating Spn Tissue Diagnosis Definitive Diagnosis Pet Accu-racy Outdated Technology Patient Underwent 18f-fdg Pet Ct Expert |
| Content Type | Text |
