NDLI: The effect of a mandibular advancement device on apneas and sleep in patients with obstructive sleep apnea. Chest.

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The effect of a mandibular advancement device on apneas and sleep in patients with obstructive sleep apnea. Chest.

Content Provider	CiteSeerX
Author	Marklund, Marie Karl, Dds Franklin, A. Sahlin, Fccp Carin Lundgren, Rune
Abstract	Objective: To evaluate the effects of a mandibular advancement device on apneas and sleep in mild, moderate, and severe obstructive sleep apnea. Design: Prospective study. Subjects: Forty-four of 47 patients included. Intervention: Individually adjusted mandibular advancement devices. Measurements: Polysomnographic sleep recordings for 1 night without the device and 1 night with it, with a median of 1 day and no changes in weight, medication, or sleep position between the recordings. Results: The device reduced the median obstructive apnea-hypopnea index from 11 (range, 7 to 19) to 5 (range, 0 to 17) (p<0.001) in 21 patients with mild sleep apnea, from 27 (range, 20 to 38) to 7 (range, 1 to 19) (p<0.001) in 15 patients with moderate sleep apnea, and from 53 (range, 44 to 66) to 14 (range, 2 to 32) (p<0.05) in 8 patients with severe sleep apnea. The arousal index decreased and the sleep stage patterns improved in all severity groups. Twenty-eight of 44 patients were successfully treated with an obstructive apnea-hypopnea index of below 10 and a subjective reduction in snoring. Nine of 16 patients with treatment failure still reported a
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Subject Keyword	Mandibular Advancement Device Obstructive Sleep Apnea Polysomnographic Sleep Recording Sleep Position Moderate Sleep Apnea Sleep Stage Pattern Treatment Failure Prospective Study Severe Sleep Apnea Arousal Index Median Obstructive Apnea-hypopnea Index Obstructive Apnea-hypopnea Index Subjective Reduction Mild Sleep Apnea Severe Obstructive Sleep Apnea Severity Group
Content Type	Text

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