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Effects of exercise and respiration on hemodynamic efficiency in cfd simulations of the total cavopulmonary connection. Annals of biomedical engineering.
| Content Provider | CiteSeerX |
|---|---|
| Author | Marsden, Alison L. Vignon-Clementel, Irene E. Chan, Frandics P. Feinstein, Jeffrey A. Taylor, Charles A. |
| Abstract | Abstract—Congenital heart defects with a single functional ventricle, such as hypoplastic left heart syndrome and tricuspid atresia, require a staged surgical approach to separate the systemic and pulmonary circulations. Ulti-mately, the venous or pulmonary side of the heart is bypassed by directly connecting the vena cava to the pulmonary arteries with a modified t-shaped junction. The Fontan procedure (total cavopulmonary connection, TCPC) completes this process of separation. To date, computational fluid dynamics (CFD) simulations in this low pressure, passive flow, intrathoracic system have neglected the pre-sumed important effects of respiration on physiology and higher ‘‘stress’ ’ states such as with exercise have never been considered. We hypothesize that incorporating effects of respiration and exercise would provide more realistic esti- |
| File Format | |
| Access Restriction | Open |
| Subject Keyword | Total Cavopulmonary Connection Cfd Simulation Biomedical Engineering Hemodynamic Efficiency Fontan Procedure Pulmonary Artery Realistic Esti Vena Cava Tricuspid Atresia Pulmonary Side Modified T-shaped Junction Single Functional Ventricle Passive Flow Stress State Pre-sumed Important Effect Pulmonary Circulation Abstract Congenital Heart Intrathoracic System Low Pressure Heart Syndrome Staged Surgical Approach Computational Fluid Dynamic |
| Content Type | Text |
