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• BRIEF REPORTS • Expression of interferon inducible protein-10 in pancreas of mice
| Content Provider | CiteSeerX |
|---|---|
| Author | Liu, Guo-Liang Liu, Dong-Juan Li, Dong Zhu, Su-Wen Liu, Su-Wen Zhu Dong-Juan |
| Abstract | AIM: To investigate the expression of interferon inducible protein-10 (IP-10) in pancreas of mice and to discuss its possible role in the pathogenesis of type 1 diabetes. METHODS: Non-obese diabetic (NOD) mice were used as experiment group and BALB/c mice as non-diabetic prone model. Immunohistochemistry method was used to evaluate the expression of IP-10 in the pancreas of NOD mice and BALB/c mice. Immunoelectron microscope was used to show the location of IP-10 in pancreatic islet β cells. RESULTS: Pancreatic islets were positively stained in all the NOD mice. Insulitis could be found in mice at the age of 4 wk. The weakly positive results were found in control group with no insulitis. Immunoelectron microscopy further |
| File Format | |
| Access Restriction | Open |
| Subject Keyword | Pancreatic Islet Experiment Group Interferon Inducible Protein-10 Immunohistochemistry Method Immunoelectron Microscopy Balb Mouse Non-obese Diabetic Brief Report Expression Pancreatic Islet Cell Non-diabetic Prone Model Possible Role Nod Mouse Immunoelectron Microscope Weakly Positive Result |
| Content Type | Text |