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Insulin resistance and the persistence of obesity from childhood into adulthood.
| Content Provider | CiteSeerX |
|---|---|
| Author | Maffeis, Claudio Moghetti, Paolo Grezzani, Alessandra Clementi, Mariangela Gaudino, Rossella Tatò€, Luciano |
| Abstract | Insulin resistance and obesity are associated in children as they are in adults. However, although insulin resistance seems to oppose further weight gain in adults, opposite results have been found in children. To investigate the relationship between childhood obesity, insulin resistance, and long-term weight gain, we selected 215 obese Caucasian children (120 males and 95 females) aged 10.5 (2.4) yr, with a relative body mass index (BMI) of 153.8 % (27.7%) and normal glucose tol-erance. Insulin resistance was assessed at baseline by using the homeostasis model assessment. Fourteen (5) years later, 103 subjects returned for a follow-up examination of height and weight. At follow-up, 37 subjects (36%) were obese (BMI> 30), 33 (32%) were overweight (25 < BMI < 30), and 33 (32%) were of normal weight (20 < BMI < 25). In a multiple regres-sion, relative BMI and insulin resistance at childhood were |
| File Format | |
| Access Restriction | Open |
| Subject Keyword | Insulin Resistance Relative Body Mass Index Opposite Result Childhood Obesity Multiple Regres-sion Relative Bmi Obese Caucasian Child Homeostasis Model Assessment Normal Glucose Tol-erance Normal Weight Follow-up Examination Weight Gain Long-term Weight Gain |
| Content Type | Text |
